NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ

NLRC5 is known for its role in inflammation and antigen presentation. Here Luan et al. find that NLRC5 protects mice from intimal hyperplasia following vascular injury, and regulates the response of vascular smooth muscle cells to injury through direct interaction with PPARγ.

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Autores principales:	Peipei Luan, Weixia Jian, Xu Xu, Wenxin Kou, Qing Yu, Handan Hu, Dali Li, Wei Wang, Mark W. Feinberg, Jianhui Zhuang, Yawei Xu, Wenhui Peng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c2aafc9bc5cd4afd8c06ce0d2c5d5732
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spelling	oai:doaj.org-article:c2aafc9bc5cd4afd8c06ce0d2c5d57322021-12-02T14:39:19ZNLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ10.1038/s41467-019-10784-y2041-1723https://doaj.org/article/c2aafc9bc5cd4afd8c06ce0d2c5d57322019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10784-yhttps://doaj.org/toc/2041-1723NLRC5 is known for its role in inflammation and antigen presentation. Here Luan et al. find that NLRC5 protects mice from intimal hyperplasia following vascular injury, and regulates the response of vascular smooth muscle cells to injury through direct interaction with PPARγ.Peipei LuanWeixia JianXu XuWenxin KouQing YuHandan HuDali LiWei WangMark W. FeinbergJianhui ZhuangYawei XuWenhui PengNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Peipei Luan Weixia Jian Xu Xu Wenxin Kou Qing Yu Handan Hu Dali Li Wei Wang Mark W. Feinberg Jianhui Zhuang Yawei Xu Wenhui Peng NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ
description	NLRC5 is known for its role in inflammation and antigen presentation. Here Luan et al. find that NLRC5 protects mice from intimal hyperplasia following vascular injury, and regulates the response of vascular smooth muscle cells to injury through direct interaction with PPARγ.
format	article
author	Peipei Luan Weixia Jian Xu Xu Wenxin Kou Qing Yu Handan Hu Dali Li Wei Wang Mark W. Feinberg Jianhui Zhuang Yawei Xu Wenhui Peng
author_facet	Peipei Luan Weixia Jian Xu Xu Wenxin Kou Qing Yu Handan Hu Dali Li Wei Wang Mark W. Feinberg Jianhui Zhuang Yawei Xu Wenhui Peng
author_sort	Peipei Luan
title	NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ
title_short	NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ
title_full	NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ
title_fullStr	NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ
title_full_unstemmed	NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ
title_sort	nlrc5 inhibits neointima formation following vascular injury and directly interacts with pparγ
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/c2aafc9bc5cd4afd8c06ce0d2c5d5732
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NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ

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