NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ
NLRC5 is known for its role in inflammation and antigen presentation. Here Luan et al. find that NLRC5 protects mice from intimal hyperplasia following vascular injury, and regulates the response of vascular smooth muscle cells to injury through direct interaction with PPARγ.
Guardado en:
Autores principales: | Peipei Luan, Weixia Jian, Xu Xu, Wenxin Kou, Qing Yu, Handan Hu, Dali Li, Wei Wang, Mark W. Feinberg, Jianhui Zhuang, Yawei Xu, Wenhui Peng |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/c2aafc9bc5cd4afd8c06ce0d2c5d5732 |
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