Theory and simulations of condensin mediated loop extrusion in DNA
How chromosomes, which are polymers with nearly billion base pairs, are packaged in the restricted nuclear volume is not well understood. Here, the authors combine polymer physics, nonequilibrium fluctuation theorem, and simulations to quantitatively predict the force-dependent velocity and step-siz...
Guardado en:
Autores principales: | Ryota Takaki, Atreya Dey, Guang Shi, D. Thirumalai |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/c2acd25da64d4e2ca116bf75bc99129d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Loop competition and extrusion model predicts CTCF interaction specificity
por: Wang Xi, et al.
Publicado: (2021) -
Modeling of DNA binding to the condensin hinge domain using molecular dynamics simulations guided by atomic force microscopy.
por: Hiroki Koide, et al.
Publicado: (2021) -
DNA looping mediates nucleosome transfer
por: Lucy D. Brennan, et al.
Publicado: (2016) -
Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
por: Osamu Iwasaki, et al.
Publicado: (2019) -
Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells
por: Sarah G Swygert, et al.
Publicado: (2021)