Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging

It was recently shown that basal cells in pseudostratified epithelia extend a long cytoplasmic process across the tight junction barrier into the lumen. Here Roy & Kim et al. show that these projections, which they call axiopodia, extend and retract over time in a c-Src and MEK-ERK-dependent man...

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Autores principales: Jeremy Roy, Bongki Kim, Eric Hill, Pablo Visconti, Dario Krapf, Claudio Vinegoni, Ralph Weissleder, Dennis Brown, Sylvie Breton
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c2b4a35c0b4d4e6a977b4fe35a92f98f
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spelling oai:doaj.org-article:c2b4a35c0b4d4e6a977b4fe35a92f98f2021-12-02T15:34:55ZTyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging10.1038/ncomms106662041-1723https://doaj.org/article/c2b4a35c0b4d4e6a977b4fe35a92f98f2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10666https://doaj.org/toc/2041-1723It was recently shown that basal cells in pseudostratified epithelia extend a long cytoplasmic process across the tight junction barrier into the lumen. Here Roy & Kim et al. show that these projections, which they call axiopodia, extend and retract over time in a c-Src and MEK-ERK-dependent manner.Jeremy RoyBongki KimEric HillPablo ViscontiDario KrapfClaudio VinegoniRalph WeisslederDennis BrownSylvie BretonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jeremy Roy
Bongki Kim
Eric Hill
Pablo Visconti
Dario Krapf
Claudio Vinegoni
Ralph Weissleder
Dennis Brown
Sylvie Breton
Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging
description It was recently shown that basal cells in pseudostratified epithelia extend a long cytoplasmic process across the tight junction barrier into the lumen. Here Roy & Kim et al. show that these projections, which they call axiopodia, extend and retract over time in a c-Src and MEK-ERK-dependent manner.
format article
author Jeremy Roy
Bongki Kim
Eric Hill
Pablo Visconti
Dario Krapf
Claudio Vinegoni
Ralph Weissleder
Dennis Brown
Sylvie Breton
author_facet Jeremy Roy
Bongki Kim
Eric Hill
Pablo Visconti
Dario Krapf
Claudio Vinegoni
Ralph Weissleder
Dennis Brown
Sylvie Breton
author_sort Jeremy Roy
title Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging
title_short Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging
title_full Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging
title_fullStr Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging
title_full_unstemmed Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging
title_sort tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/c2b4a35c0b4d4e6a977b4fe35a92f98f
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