Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging
It was recently shown that basal cells in pseudostratified epithelia extend a long cytoplasmic process across the tight junction barrier into the lumen. Here Roy & Kim et al. show that these projections, which they call axiopodia, extend and retract over time in a c-Src and MEK-ERK-dependent man...
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Nature Portfolio
2016
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oai:doaj.org-article:c2b4a35c0b4d4e6a977b4fe35a92f98f2021-12-02T15:34:55ZTyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging10.1038/ncomms106662041-1723https://doaj.org/article/c2b4a35c0b4d4e6a977b4fe35a92f98f2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10666https://doaj.org/toc/2041-1723It was recently shown that basal cells in pseudostratified epithelia extend a long cytoplasmic process across the tight junction barrier into the lumen. Here Roy & Kim et al. show that these projections, which they call axiopodia, extend and retract over time in a c-Src and MEK-ERK-dependent manner.Jeremy RoyBongki KimEric HillPablo ViscontiDario KrapfClaudio VinegoniRalph WeisslederDennis BrownSylvie BretonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016) |
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Science Q Jeremy Roy Bongki Kim Eric Hill Pablo Visconti Dario Krapf Claudio Vinegoni Ralph Weissleder Dennis Brown Sylvie Breton Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging |
description |
It was recently shown that basal cells in pseudostratified epithelia extend a long cytoplasmic process across the tight junction barrier into the lumen. Here Roy & Kim et al. show that these projections, which they call axiopodia, extend and retract over time in a c-Src and MEK-ERK-dependent manner. |
format |
article |
author |
Jeremy Roy Bongki Kim Eric Hill Pablo Visconti Dario Krapf Claudio Vinegoni Ralph Weissleder Dennis Brown Sylvie Breton |
author_facet |
Jeremy Roy Bongki Kim Eric Hill Pablo Visconti Dario Krapf Claudio Vinegoni Ralph Weissleder Dennis Brown Sylvie Breton |
author_sort |
Jeremy Roy |
title |
Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging |
title_short |
Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging |
title_full |
Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging |
title_fullStr |
Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging |
title_full_unstemmed |
Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging |
title_sort |
tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/c2b4a35c0b4d4e6a977b4fe35a92f98f |
work_keys_str_mv |
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1718386742899245056 |