Analysis of Plasmodium vivax schizont transcriptomes from field isolates reveals heterogeneity of expression of genes involved in host-parasite interactions

Abstract Plasmodium vivax gene regulation remains difficult to study due to the lack of a robust in vitro culture method, low parasite densities in peripheral circulation and asynchronous parasite development. We adapted an RNA-seq protocol “DAFT-seq” to sequence the transcriptome of four P. vivax f...

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Autores principales: Sasha V. Siegel, Lia Chappell, Jessica B. Hostetler, Chanaki Amaratunga, Seila Suon, Ulrike Böhme, Matthew Berriman, Rick M. Fairhurst, Julian C. Rayner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c2c28e9b7b754adc9f200b9d0768dd5b
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