The Maintenance of Telomere Length in CD28+ T Cells During T Lymphocyte Stimulation

The Maintenance of Telomere Length in CD28+ T Cells During T Lymphocyte Stimulation

Abstract Telomerase activity is not readily detected in resting human T lymphocytes, however upon antigen presentation, telomerase is transiently upregulated. Presently, it is not known if telomerase activation is necessary for the proliferation of T cells or for the maintenance of telomere lengths....

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Autores principales: Ejun (Elijah) Huang, Enzo Tedone, Ryan O’Hara, Crystal Cornelius, Tsung-Po Lai, Andrew Ludlow, Woodring E. Wright, Jerry W. Shay
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/c2dc49f6b23047739c01bec8a08dc03e
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