Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes
Latika Sibal1, Sharad C Agarwal2, Philip D Home21Wolfson Diabetes and Endocrine Clinic, Addenbrooke's Hospital, Cambridge, UK; 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UKBackground: Diabetes mellitus is associated with a high risk of cardiovascular dise...
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Dove Medical Press
2011
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oai:doaj.org-article:c2e71cbffcc145139a88fc13579e73932021-12-02T01:25:57ZCarotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes1178-7007https://doaj.org/article/c2e71cbffcc145139a88fc13579e73932011-01-01T00:00:00Zhttp://www.dovepress.com/carotid-intima-media-thickness-as-a-surrogate-marker-of-cardiovascular-a6078https://doaj.org/toc/1178-7007Latika Sibal1, Sharad C Agarwal2, Philip D Home21Wolfson Diabetes and Endocrine Clinic, Addenbrooke's Hospital, Cambridge, UK; 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UKBackground: Diabetes mellitus is associated with a high risk of cardiovascular disease. Carotid intima-media thickness (CIMT) is increasingly used as a surrogate marker for atherosclerosis. Its use relies on its ability to predict future clinical cardiovascular end points.Methods: This review examines the evidence linking CIMT as a surrogate marker of vascular complications in people with type 1 and type 2 diabetes. We have also reviewed the various treatment strategies which have been shown to influence CIMT.Conclusions: CIMT measurement is an effective, noninvasive tool which can assist in identifying people with diabetes who are at higher risk of developing microvascular and macrovascular complications. It may also help to evaluate the effectiveness of various treatment strategies used to treat people with diabetes.Keywords: carotid, intima-media thickness, CIMT, diabetes Latika SibalSharad C AgarwalPhilip D HomeDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2011, Iss default, Pp 23-34 (2011) |
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Specialties of internal medicine RC581-951 Latika Sibal Sharad C Agarwal Philip D Home Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
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Latika Sibal1, Sharad C Agarwal2, Philip D Home21Wolfson Diabetes and Endocrine Clinic, Addenbrooke's Hospital, Cambridge, UK; 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UKBackground: Diabetes mellitus is associated with a high risk of cardiovascular disease. Carotid intima-media thickness (CIMT) is increasingly used as a surrogate marker for atherosclerosis. Its use relies on its ability to predict future clinical cardiovascular end points.Methods: This review examines the evidence linking CIMT as a surrogate marker of vascular complications in people with type 1 and type 2 diabetes. We have also reviewed the various treatment strategies which have been shown to influence CIMT.Conclusions: CIMT measurement is an effective, noninvasive tool which can assist in identifying people with diabetes who are at higher risk of developing microvascular and macrovascular complications. It may also help to evaluate the effectiveness of various treatment strategies used to treat people with diabetes.Keywords: carotid, intima-media thickness, CIMT, diabetes |
format |
article |
author |
Latika Sibal Sharad C Agarwal Philip D Home |
author_facet |
Latika Sibal Sharad C Agarwal Philip D Home |
author_sort |
Latika Sibal |
title |
Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
title_short |
Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
title_full |
Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
title_fullStr |
Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
title_full_unstemmed |
Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
title_sort |
carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
publisher |
Dove Medical Press |
publishDate |
2011 |
url |
https://doaj.org/article/c2e71cbffcc145139a88fc13579e7393 |
work_keys_str_mv |
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