Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes

Latika Sibal1, Sharad C Agarwal2, Philip D Home21Wolfson Diabetes and Endocrine Clinic, Addenbrooke's Hospital, Cambridge, UK; 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UKBackground: Diabetes mellitus is associated with a high risk of cardiovascular dise...

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Autores principales: Latika Sibal, Sharad C Agarwal, Philip D Home
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Publicado: Dove Medical Press 2011
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spelling oai:doaj.org-article:c2e71cbffcc145139a88fc13579e73932021-12-02T01:25:57ZCarotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes1178-7007https://doaj.org/article/c2e71cbffcc145139a88fc13579e73932011-01-01T00:00:00Zhttp://www.dovepress.com/carotid-intima-media-thickness-as-a-surrogate-marker-of-cardiovascular-a6078https://doaj.org/toc/1178-7007Latika Sibal1, Sharad C Agarwal2, Philip D Home21Wolfson Diabetes and Endocrine Clinic, Addenbrooke's Hospital, Cambridge, UK; 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UKBackground: Diabetes mellitus is associated with a high risk of cardiovascular disease. Carotid intima-media thickness (CIMT) is increasingly used as a surrogate marker for atherosclerosis. Its use relies on its ability to predict future clinical cardiovascular end points.Methods: This review examines the evidence linking CIMT as a surrogate marker of vascular complications in people with type 1 and type 2 diabetes. We have also reviewed the various treatment strategies which have been shown to influence CIMT.Conclusions: CIMT measurement is an effective, noninvasive tool which can assist in identifying people with diabetes who are at higher risk of developing microvascular and macrovascular complications. It may also help to evaluate the effectiveness of various treatment strategies used to treat people with diabetes.Keywords: carotid, intima-media thickness, CIMT, diabetes Latika SibalSharad C AgarwalPhilip D HomeDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2011, Iss default, Pp 23-34 (2011)
institution DOAJ
collection DOAJ
language EN
topic Specialties of internal medicine
RC581-951
spellingShingle Specialties of internal medicine
RC581-951
Latika Sibal
Sharad C Agarwal
Philip D Home
Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes
description Latika Sibal1, Sharad C Agarwal2, Philip D Home21Wolfson Diabetes and Endocrine Clinic, Addenbrooke's Hospital, Cambridge, UK; 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UKBackground: Diabetes mellitus is associated with a high risk of cardiovascular disease. Carotid intima-media thickness (CIMT) is increasingly used as a surrogate marker for atherosclerosis. Its use relies on its ability to predict future clinical cardiovascular end points.Methods: This review examines the evidence linking CIMT as a surrogate marker of vascular complications in people with type 1 and type 2 diabetes. We have also reviewed the various treatment strategies which have been shown to influence CIMT.Conclusions: CIMT measurement is an effective, noninvasive tool which can assist in identifying people with diabetes who are at higher risk of developing microvascular and macrovascular complications. It may also help to evaluate the effectiveness of various treatment strategies used to treat people with diabetes.Keywords: carotid, intima-media thickness, CIMT, diabetes
format article
author Latika Sibal
Sharad C Agarwal
Philip D Home
author_facet Latika Sibal
Sharad C Agarwal
Philip D Home
author_sort Latika Sibal
title Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes
title_short Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes
title_full Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes
title_fullStr Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes
title_full_unstemmed Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes
title_sort carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/c2e71cbffcc145139a88fc13579e7393
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AT sharadcagarwal carotidintimamediathicknessasasurrogatemarkerofcardiovasculardiseaseindiabetes
AT philipdhome carotidintimamediathicknessasasurrogatemarkerofcardiovasculardiseaseindiabetes
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