V2a interneuron diversity tailors spinal circuit organization to control the vigor of locomotor movements

Locomotor circuits in the spinal cord produce precise movements with variations in timing and vigor. Here, the authors report that such motor flexibility is generated through the specificity of connections between subtypes of V2a interneurons and motoneuron populations and their distinct plasticity...

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Autores principales: Jianren Song, Elin Dahlberg, Abdeljabbar El Manira
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c2e86865363741b69ea95833620b6b63
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Sumario:Locomotor circuits in the spinal cord produce precise movements with variations in timing and vigor. Here, the authors report that such motor flexibility is generated through the specificity of connections between subtypes of V2a interneurons and motoneuron populations and their distinct plasticity mechanisms.