LMO7 deficiency reveals the significance of the cuticular plate for hearing function

In contrast to the extensively studied mechanosensory hair bundle, the cuticular plate is not as well understood. In this study, authors describe the discovery of a hair cell protein called LIM only protein 7, which is localized in the cuticular plate and the cell junction and may play a role in age...

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Autores principales: Ting-Ting Du, James B. Dewey, Elizabeth L. Wagner, Runjia Cui, Jinho Heo, Jeong-Jin Park, Shimon P. Francis, Edward Perez-Reyes, Stacey J. Guillot, Nicholas E. Sherman, Wenhao Xu, John S Oghalai, Bechara Kachar, Jung-Bum Shin
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/c2ec714b45bc41bf96953f0212beec8a
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spelling oai:doaj.org-article:c2ec714b45bc41bf96953f0212beec8a2021-12-02T14:38:41ZLMO7 deficiency reveals the significance of the cuticular plate for hearing function10.1038/s41467-019-09074-42041-1723https://doaj.org/article/c2ec714b45bc41bf96953f0212beec8a2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09074-4https://doaj.org/toc/2041-1723In contrast to the extensively studied mechanosensory hair bundle, the cuticular plate is not as well understood. In this study, authors describe the discovery of a hair cell protein called LIM only protein 7, which is localized in the cuticular plate and the cell junction and may play a role in age-related deafness.Ting-Ting DuJames B. DeweyElizabeth L. WagnerRunjia CuiJinho HeoJeong-Jin ParkShimon P. FrancisEdward Perez-ReyesStacey J. GuillotNicholas E. ShermanWenhao XuJohn S OghalaiBechara KacharJung-Bum ShinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ting-Ting Du
James B. Dewey
Elizabeth L. Wagner
Runjia Cui
Jinho Heo
Jeong-Jin Park
Shimon P. Francis
Edward Perez-Reyes
Stacey J. Guillot
Nicholas E. Sherman
Wenhao Xu
John S Oghalai
Bechara Kachar
Jung-Bum Shin
LMO7 deficiency reveals the significance of the cuticular plate for hearing function
description In contrast to the extensively studied mechanosensory hair bundle, the cuticular plate is not as well understood. In this study, authors describe the discovery of a hair cell protein called LIM only protein 7, which is localized in the cuticular plate and the cell junction and may play a role in age-related deafness.
format article
author Ting-Ting Du
James B. Dewey
Elizabeth L. Wagner
Runjia Cui
Jinho Heo
Jeong-Jin Park
Shimon P. Francis
Edward Perez-Reyes
Stacey J. Guillot
Nicholas E. Sherman
Wenhao Xu
John S Oghalai
Bechara Kachar
Jung-Bum Shin
author_facet Ting-Ting Du
James B. Dewey
Elizabeth L. Wagner
Runjia Cui
Jinho Heo
Jeong-Jin Park
Shimon P. Francis
Edward Perez-Reyes
Stacey J. Guillot
Nicholas E. Sherman
Wenhao Xu
John S Oghalai
Bechara Kachar
Jung-Bum Shin
author_sort Ting-Ting Du
title LMO7 deficiency reveals the significance of the cuticular plate for hearing function
title_short LMO7 deficiency reveals the significance of the cuticular plate for hearing function
title_full LMO7 deficiency reveals the significance of the cuticular plate for hearing function
title_fullStr LMO7 deficiency reveals the significance of the cuticular plate for hearing function
title_full_unstemmed LMO7 deficiency reveals the significance of the cuticular plate for hearing function
title_sort lmo7 deficiency reveals the significance of the cuticular plate for hearing function
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/c2ec714b45bc41bf96953f0212beec8a
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