The Barriers, Challenges, and Strategies of COVID-19 (SARS-CoV-2) Vaccine Acceptance: A Concurrent Mixed-Method Study in Tehran City, Iran

Acceptance and willingness to receive the vaccine are among the main factors in the success or failure of a health system in implementing the vaccination program. The present study was conducted in Tehran, the political and economic capital of Iran, to determine the acceptance of the COVID-19 vaccin...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hamid Reza Khankeh, Mehrdad Farrokhi, Mohammad Saeed Khanjani, Yadollah Abolfathi Momtaz, Ameneh Setareh Forouzan, Mehdi Norouzi, Shokoufeh Ahmadi, Gholamreza Ghaedamini Harouni, Juliet Roudini, Elham Ghanaatpisheh, Arya Hamedanchi, Mohammad Pourebrahimi, Fardin Alipour, Maryam Ranjbar, Mehrdad Naghikhani, Mohammad Saatchi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	coronavirus disease 2019 (COVID-19) vaccine vaccine hesitancy vaccination acceptance vaccine efficacy challenges trust Medicine R
Acceso en línea:	https://doaj.org/article/c2f536b3c867458597e80cdb8e08c8f5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c2f536b3c867458597e80cdb8e08c8f5
record_format	dspace
spelling	oai:doaj.org-article:c2f536b3c867458597e80cdb8e08c8f52021-11-25T19:10:31ZThe Barriers, Challenges, and Strategies of COVID-19 (SARS-CoV-2) Vaccine Acceptance: A Concurrent Mixed-Method Study in Tehran City, Iran10.3390/vaccines91112482076-393Xhttps://doaj.org/article/c2f536b3c867458597e80cdb8e08c8f52021-10-01T00:00:00Zhttps://www.mdpi.com/2076-393X/9/11/1248https://doaj.org/toc/2076-393XAcceptance and willingness to receive the vaccine are among the main factors in the success or failure of a health system in implementing the vaccination program. The present study was conducted in Tehran, the political and economic capital of Iran, to determine the acceptance of the COVID-19 vaccine and identify its associated factors, and explain the most important barriers and acceptance strategies for vaccination. This research was a concurrent quantitative and qualitative mixed-method study. In the quantitative part, 1200 individuals aged more than 18 years were selected from the households in 22 districts of Tehran City, with a multistage stratified cluster sampling method. Two questionnaires were used to evaluate the acceptance of the COVID-19 vaccine and vaccine acceptance determinants. The qualitative content analysis method addressed the influencing factors, as well as challenges and strategies related to the acceptance of the COVID-19 vaccine in four groups of Tehran inhabitants: the elderly, people with underlying diseases, healthcare workers, and the general population. The related data were simultaneously collected by applying in-depth semi-structural interviews and a data analysis process. Furthermore, we used the Graneheim and Lundman method for data analysis. We analyzed the data of 1200 people with a mean (SD) age of 46.4 (11.1) years, and approximately 58% of them were men. The vaccine acceptance was 83.6% (95% CI: 81.3–85.9). Among those who welcomed vaccination, 58% preferred the imported vaccines, 25% the Iranian ones, and 17% both. There was a significant association between the variables of age (adjusted odds ratio [AOR] = 1.72, 95% CI: 1.01–2.93), being single (AOR = 0.54, 95% CI: 0.41–0.91), moderate pharmacotherapy adherence (AOR = 0.58, 95% CI: 0.4–0.85), and the willingness to receive COVID-19 vaccine. Qualitative study after interviewing 45 people from four study groups showed an insufficient social trust in healthcare system officials, pharmaceutical and vaccine production companies; distrust in the effectiveness of the vaccines, concerns about the vaccine adverse effects, being tracked by microchips after vaccination, traditional anti-vaccination movements, the feeling the inessentiality of vaccination, and uncertainty about the fair distribution of the vaccine. These concerns were the main challenges addressed by the study groups. A good proportion of Tehran residents reported their willingness to receive the COVID-19 vaccine. Additionally, they expressed their critical concerns, such as insufficient trust in the healthcare system, vaccine safeties, and adverse effects that were the significant barriers to vaccine acceptance. It seems that conflicts raised by the shortage of vaccines and their import due to the sanctions have led to intense desire and demand in the general population, and especially the elderly, for vaccination. Besides, vaccination phobia in some individuals requires further investigations.Hamid Reza KhankehMehrdad FarrokhiMohammad Saeed KhanjaniYadollah Abolfathi MomtazAmeneh Setareh ForouzanMehdi NorouziShokoufeh AhmadiGholamreza Ghaedamini HarouniJuliet RoudiniElham GhanaatpishehArya HamedanchiMohammad PourebrahimiFardin AlipourMaryam RanjbarMehrdad NaghikhaniMohammad SaatchiMDPI AGarticlecoronavirus disease 2019 (COVID-19) vaccinevaccine hesitancyvaccination acceptancevaccine efficacychallengestrustMedicineRENVaccines, Vol 9, Iss 1248, p 1248 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	coronavirus disease 2019 (COVID-19) vaccine vaccine hesitancy vaccination acceptance vaccine efficacy challenges trust Medicine R
spellingShingle	coronavirus disease 2019 (COVID-19) vaccine vaccine hesitancy vaccination acceptance vaccine efficacy challenges trust Medicine R Hamid Reza Khankeh Mehrdad Farrokhi Mohammad Saeed Khanjani Yadollah Abolfathi Momtaz Ameneh Setareh Forouzan Mehdi Norouzi Shokoufeh Ahmadi Gholamreza Ghaedamini Harouni Juliet Roudini Elham Ghanaatpisheh Arya Hamedanchi Mohammad Pourebrahimi Fardin Alipour Maryam Ranjbar Mehrdad Naghikhani Mohammad Saatchi The Barriers, Challenges, and Strategies of COVID-19 (SARS-CoV-2) Vaccine Acceptance: A Concurrent Mixed-Method Study in Tehran City, Iran
description	Acceptance and willingness to receive the vaccine are among the main factors in the success or failure of a health system in implementing the vaccination program. The present study was conducted in Tehran, the political and economic capital of Iran, to determine the acceptance of the COVID-19 vaccine and identify its associated factors, and explain the most important barriers and acceptance strategies for vaccination. This research was a concurrent quantitative and qualitative mixed-method study. In the quantitative part, 1200 individuals aged more than 18 years were selected from the households in 22 districts of Tehran City, with a multistage stratified cluster sampling method. Two questionnaires were used to evaluate the acceptance of the COVID-19 vaccine and vaccine acceptance determinants. The qualitative content analysis method addressed the influencing factors, as well as challenges and strategies related to the acceptance of the COVID-19 vaccine in four groups of Tehran inhabitants: the elderly, people with underlying diseases, healthcare workers, and the general population. The related data were simultaneously collected by applying in-depth semi-structural interviews and a data analysis process. Furthermore, we used the Graneheim and Lundman method for data analysis. We analyzed the data of 1200 people with a mean (SD) age of 46.4 (11.1) years, and approximately 58% of them were men. The vaccine acceptance was 83.6% (95% CI: 81.3–85.9). Among those who welcomed vaccination, 58% preferred the imported vaccines, 25% the Iranian ones, and 17% both. There was a significant association between the variables of age (adjusted odds ratio [AOR] = 1.72, 95% CI: 1.01–2.93), being single (AOR = 0.54, 95% CI: 0.41–0.91), moderate pharmacotherapy adherence (AOR = 0.58, 95% CI: 0.4–0.85), and the willingness to receive COVID-19 vaccine. Qualitative study after interviewing 45 people from four study groups showed an insufficient social trust in healthcare system officials, pharmaceutical and vaccine production companies; distrust in the effectiveness of the vaccines, concerns about the vaccine adverse effects, being tracked by microchips after vaccination, traditional anti-vaccination movements, the feeling the inessentiality of vaccination, and uncertainty about the fair distribution of the vaccine. These concerns were the main challenges addressed by the study groups. A good proportion of Tehran residents reported their willingness to receive the COVID-19 vaccine. Additionally, they expressed their critical concerns, such as insufficient trust in the healthcare system, vaccine safeties, and adverse effects that were the significant barriers to vaccine acceptance. It seems that conflicts raised by the shortage of vaccines and their import due to the sanctions have led to intense desire and demand in the general population, and especially the elderly, for vaccination. Besides, vaccination phobia in some individuals requires further investigations.
format	article
author	Hamid Reza Khankeh Mehrdad Farrokhi Mohammad Saeed Khanjani Yadollah Abolfathi Momtaz Ameneh Setareh Forouzan Mehdi Norouzi Shokoufeh Ahmadi Gholamreza Ghaedamini Harouni Juliet Roudini Elham Ghanaatpisheh Arya Hamedanchi Mohammad Pourebrahimi Fardin Alipour Maryam Ranjbar Mehrdad Naghikhani Mohammad Saatchi
author_facet	Hamid Reza Khankeh Mehrdad Farrokhi Mohammad Saeed Khanjani Yadollah Abolfathi Momtaz Ameneh Setareh Forouzan Mehdi Norouzi Shokoufeh Ahmadi Gholamreza Ghaedamini Harouni Juliet Roudini Elham Ghanaatpisheh Arya Hamedanchi Mohammad Pourebrahimi Fardin Alipour Maryam Ranjbar Mehrdad Naghikhani Mohammad Saatchi
author_sort	Hamid Reza Khankeh
title	The Barriers, Challenges, and Strategies of COVID-19 (SARS-CoV-2) Vaccine Acceptance: A Concurrent Mixed-Method Study in Tehran City, Iran
title_short	The Barriers, Challenges, and Strategies of COVID-19 (SARS-CoV-2) Vaccine Acceptance: A Concurrent Mixed-Method Study in Tehran City, Iran
title_full	The Barriers, Challenges, and Strategies of COVID-19 (SARS-CoV-2) Vaccine Acceptance: A Concurrent Mixed-Method Study in Tehran City, Iran
title_fullStr	The Barriers, Challenges, and Strategies of COVID-19 (SARS-CoV-2) Vaccine Acceptance: A Concurrent Mixed-Method Study in Tehran City, Iran
title_full_unstemmed	The Barriers, Challenges, and Strategies of COVID-19 (SARS-CoV-2) Vaccine Acceptance: A Concurrent Mixed-Method Study in Tehran City, Iran
title_sort	barriers, challenges, and strategies of covid-19 (sars-cov-2) vaccine acceptance: a concurrent mixed-method study in tehran city, iran
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/c2f536b3c867458597e80cdb8e08c8f5
work_keys_str_mv	AT hamidrezakhankeh thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mehrdadfarrokhi thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mohammadsaeedkhanjani thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT yadollahabolfathimomtaz thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT amenehsetarehforouzan thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mehdinorouzi thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT shokoufehahmadi thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT gholamrezaghaedaminiharouni thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT julietroudini thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT elhamghanaatpisheh thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT aryahamedanchi thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mohammadpourebrahimi thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT fardinalipour thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT maryamranjbar thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mehrdadnaghikhani thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mohammadsaatchi thebarrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT hamidrezakhankeh barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mehrdadfarrokhi barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mohammadsaeedkhanjani barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT yadollahabolfathimomtaz barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT amenehsetarehforouzan barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mehdinorouzi barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT shokoufehahmadi barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT gholamrezaghaedaminiharouni barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT julietroudini barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT elhamghanaatpisheh barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT aryahamedanchi barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mohammadpourebrahimi barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT fardinalipour barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT maryamranjbar barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mehrdadnaghikhani barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran AT mohammadsaatchi barrierschallengesandstrategiesofcovid19sarscov2vaccineacceptanceaconcurrentmixedmethodstudyintehrancityiran
_version_	1718410240561512448

The Barriers, Challenges, and Strategies of COVID-19 (SARS-CoV-2) Vaccine Acceptance: A Concurrent Mixed-Method Study in Tehran City, Iran

Ejemplares similares