Analyzing the Photoprotection Efficiency of Sunscreens Containing Antioxidants under Disinfection Conditions

Sunscreens ensure thorough protection against sunburn. The delivery of UV filters into the stratum corneum and viable epidermis could be reduced by the use of antioxidants (such as β-carotene and trans-resveratrol, alone or combined). The presence/absence of antioxidants (trans-resveratrol and β-car...

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Autores principales:	Robert Sotler, Metka Adamič, Kristjan Jarni, Raja Dahmane, Polonca Trebše, Mojca Bavcon Kralj
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	ultraviolet radiation UV filter benzophenone-3 trans-resveratrol β-carotene chlorinated products Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/c2f64e3e094541bfbd8f94940ff136f1
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id	oai:doaj.org-article:c2f64e3e094541bfbd8f94940ff136f1
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spelling	oai:doaj.org-article:c2f64e3e094541bfbd8f94940ff136f12021-11-25T16:27:12ZAnalyzing the Photoprotection Efficiency of Sunscreens Containing Antioxidants under Disinfection Conditions10.3390/antiox101117202076-3921https://doaj.org/article/c2f64e3e094541bfbd8f94940ff136f12021-10-01T00:00:00Zhttps://www.mdpi.com/2076-3921/10/11/1720https://doaj.org/toc/2076-3921Sunscreens ensure thorough protection against sunburn. The delivery of UV filters into the stratum corneum and viable epidermis could be reduced by the use of antioxidants (such as β-carotene and trans-resveratrol, alone or combined). The presence/absence of antioxidants (trans-resveratrol and β-carotene) in formulations containing benzophenone-3 (UV-filter) and their efficiency under disinfection and neutral conditions are studied and compared. The trial was conducted on 38 people. The prepared ointments were applied to the participants’ forearms, irradiated and monitored by reflectance colorimetry after 0, 4, 6, and 8 min. Descriptive statistics were used to describe the skin color’s main characteristics and the F-ratio was used to test overall differences. The ointments containing antioxidants and benzophenone-3 were the most efficient, followed by those with benzophenone-3 alone. It was proven that photoprotection with benzophenone-3 is still effective, despite the formation of its chlorinated products. Due to the short time of exposure to disinfecting conditions, it could be assumed that benzophenone-3 was only partially chlorinated. This clinical study demonstrated that formulations containing antioxidants are likely to be more suitable for protecting skin against UVB irradiation than a UV filter alone.Robert SotlerMetka AdamičKristjan JarniRaja DahmanePolonca TrebšeMojca Bavcon KraljMDPI AGarticleultraviolet radiationUV filterbenzophenone-3trans-resveratrolβ-carotenechlorinated productsTherapeutics. PharmacologyRM1-950ENAntioxidants, Vol 10, Iss 1720, p 1720 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	ultraviolet radiation UV filter benzophenone-3 trans-resveratrol β-carotene chlorinated products Therapeutics. Pharmacology RM1-950
spellingShingle	ultraviolet radiation UV filter benzophenone-3 trans-resveratrol β-carotene chlorinated products Therapeutics. Pharmacology RM1-950 Robert Sotler Metka Adamič Kristjan Jarni Raja Dahmane Polonca Trebše Mojca Bavcon Kralj Analyzing the Photoprotection Efficiency of Sunscreens Containing Antioxidants under Disinfection Conditions
description	Sunscreens ensure thorough protection against sunburn. The delivery of UV filters into the stratum corneum and viable epidermis could be reduced by the use of antioxidants (such as β-carotene and trans-resveratrol, alone or combined). The presence/absence of antioxidants (trans-resveratrol and β-carotene) in formulations containing benzophenone-3 (UV-filter) and their efficiency under disinfection and neutral conditions are studied and compared. The trial was conducted on 38 people. The prepared ointments were applied to the participants’ forearms, irradiated and monitored by reflectance colorimetry after 0, 4, 6, and 8 min. Descriptive statistics were used to describe the skin color’s main characteristics and the F-ratio was used to test overall differences. The ointments containing antioxidants and benzophenone-3 were the most efficient, followed by those with benzophenone-3 alone. It was proven that photoprotection with benzophenone-3 is still effective, despite the formation of its chlorinated products. Due to the short time of exposure to disinfecting conditions, it could be assumed that benzophenone-3 was only partially chlorinated. This clinical study demonstrated that formulations containing antioxidants are likely to be more suitable for protecting skin against UVB irradiation than a UV filter alone.
format	article
author	Robert Sotler Metka Adamič Kristjan Jarni Raja Dahmane Polonca Trebše Mojca Bavcon Kralj
author_facet	Robert Sotler Metka Adamič Kristjan Jarni Raja Dahmane Polonca Trebše Mojca Bavcon Kralj
author_sort	Robert Sotler
title	Analyzing the Photoprotection Efficiency of Sunscreens Containing Antioxidants under Disinfection Conditions
title_short	Analyzing the Photoprotection Efficiency of Sunscreens Containing Antioxidants under Disinfection Conditions
title_full	Analyzing the Photoprotection Efficiency of Sunscreens Containing Antioxidants under Disinfection Conditions
title_fullStr	Analyzing the Photoprotection Efficiency of Sunscreens Containing Antioxidants under Disinfection Conditions
title_full_unstemmed	Analyzing the Photoprotection Efficiency of Sunscreens Containing Antioxidants under Disinfection Conditions
title_sort	analyzing the photoprotection efficiency of sunscreens containing antioxidants under disinfection conditions
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/c2f64e3e094541bfbd8f94940ff136f1
work_keys_str_mv	AT robertsotler analyzingthephotoprotectionefficiencyofsunscreenscontainingantioxidantsunderdisinfectionconditions AT metkaadamic analyzingthephotoprotectionefficiencyofsunscreenscontainingantioxidantsunderdisinfectionconditions AT kristjanjarni analyzingthephotoprotectionefficiencyofsunscreenscontainingantioxidantsunderdisinfectionconditions AT rajadahmane analyzingthephotoprotectionefficiencyofsunscreenscontainingantioxidantsunderdisinfectionconditions AT poloncatrebse analyzingthephotoprotectionefficiencyofsunscreenscontainingantioxidantsunderdisinfectionconditions AT mojcabavconkralj analyzingthephotoprotectionefficiencyofsunscreenscontainingantioxidantsunderdisinfectionconditions
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Analyzing the Photoprotection Efficiency of Sunscreens Containing Antioxidants under Disinfection Conditions

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