The effect of long-term use of intranasal steroids on intraocular pressure

Ali Şimşek,1 Cem Bayraktar,2 Sedat Doğan,2 Mehmet Karataş,2 Yasin Sarıkaya2 1Department of Ophthalmology, 2Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, Adıyaman, Turkey Abstract: Long-term use of topical nasal steroids (especially older g...

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Autores principales: Şimşek A, Bayraktar C, Doğan S, Karataş M, Sarıkaya Y
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Lenguaje:EN
Publicado: Dove Medical Press 2016
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Acceso en línea:https://doaj.org/article/c2f8129d999b433b8d53ae0578f81781
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spelling oai:doaj.org-article:c2f8129d999b433b8d53ae0578f817812021-12-02T00:09:31ZThe effect of long-term use of intranasal steroids on intraocular pressure1177-5483https://doaj.org/article/c2f8129d999b433b8d53ae0578f817812016-06-01T00:00:00Zhttps://www.dovepress.com/the-effect-of-long-term-use-of-intranasal-steroids-on-intraocular-pres-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Ali Şimşek,1 Cem Bayraktar,2 Sedat Doğan,2 Mehmet Karataş,2 Yasin Sarıkaya2 1Department of Ophthalmology, 2Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, Adıyaman, Turkey Abstract: Long-term use of topical nasal steroids (especially older generation steroids) has been shown to elevate intraocular pressure (IOP), but newer intranasal steroids are thought to have a minimal effect on IOP because of their low bioavailability. This study aimed to investigate alterations in IOP with two commonly used intranasal steroids for a 6-month period of time. One-hundred allergic rhinitis patients, divided equally into two groups, used mometasone furoate and fluticasone furoate intranasal steroids for 6 months. IOPs were measured before treatment and repeated at the 3rd, 6th, 12th, and 24th weeks of treatment. The IOPs of the groups were then compared. No statistically significant alteration was observed between the groups during the treatment time period. It was found that new generation intranasal steroids can be used safely, and there may not be an increased risk of IOP elevation in prolonged use in normal healthy people. Keywords: intraocular pressure, nasal steroids, prolonged use, allergic rhinitisŞimşek ABayraktar CDoğan SKarataş MSarıkaya YDove Medical Pressarticleintraocular pressurenasal steroidsprolonged useallergic rhinitisOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 1079-1082 (2016)
institution DOAJ
collection DOAJ
language EN
topic intraocular pressure
nasal steroids
prolonged use
allergic rhinitis
Ophthalmology
RE1-994
spellingShingle intraocular pressure
nasal steroids
prolonged use
allergic rhinitis
Ophthalmology
RE1-994
Şimşek A
Bayraktar C
Doğan S
Karataş M
Sarıkaya Y
The effect of long-term use of intranasal steroids on intraocular pressure
description Ali Şimşek,1 Cem Bayraktar,2 Sedat Doğan,2 Mehmet Karataş,2 Yasin Sarıkaya2 1Department of Ophthalmology, 2Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, Adıyaman, Turkey Abstract: Long-term use of topical nasal steroids (especially older generation steroids) has been shown to elevate intraocular pressure (IOP), but newer intranasal steroids are thought to have a minimal effect on IOP because of their low bioavailability. This study aimed to investigate alterations in IOP with two commonly used intranasal steroids for a 6-month period of time. One-hundred allergic rhinitis patients, divided equally into two groups, used mometasone furoate and fluticasone furoate intranasal steroids for 6 months. IOPs were measured before treatment and repeated at the 3rd, 6th, 12th, and 24th weeks of treatment. The IOPs of the groups were then compared. No statistically significant alteration was observed between the groups during the treatment time period. It was found that new generation intranasal steroids can be used safely, and there may not be an increased risk of IOP elevation in prolonged use in normal healthy people. Keywords: intraocular pressure, nasal steroids, prolonged use, allergic rhinitis
format article
author Şimşek A
Bayraktar C
Doğan S
Karataş M
Sarıkaya Y
author_facet Şimşek A
Bayraktar C
Doğan S
Karataş M
Sarıkaya Y
author_sort Şimşek A
title The effect of long-term use of intranasal steroids on intraocular pressure
title_short The effect of long-term use of intranasal steroids on intraocular pressure
title_full The effect of long-term use of intranasal steroids on intraocular pressure
title_fullStr The effect of long-term use of intranasal steroids on intraocular pressure
title_full_unstemmed The effect of long-term use of intranasal steroids on intraocular pressure
title_sort effect of long-term use of intranasal steroids on intraocular pressure
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/c2f8129d999b433b8d53ae0578f81781
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