Prognostic significance of Troponin I in patients undergoing primary percutaneous coronary intervention

This observational study investigates the prognostic significance of troponin I in patients undergoing primary percutaneous intervention (pPCI). Sequential cardiac biomarker sampling of the enrolled patients (n = 167) was performed on admission and at 6,12,24 and 48 h. Clinical characteristics, majo...

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Autores principales:	Pratik Sudhir Sane, DNB, V Manoj, MD, Rufus Demel, MD, S. Vijaykumar, MD, DM ,FNB, Ajit.S. Mullasari, MD, DNB, DM , FRCP
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Troponin I Primary PCI MACCE Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/c3012583a9284945a96ae96ffc1e242f
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spelling	oai:doaj.org-article:c3012583a9284945a96ae96ffc1e242f2021-12-02T04:57:58ZPrognostic significance of Troponin I in patients undergoing primary percutaneous coronary intervention0019-483210.1016/j.ihj.2021.09.004https://doaj.org/article/c3012583a9284945a96ae96ffc1e242f2021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S0019483221001917https://doaj.org/toc/0019-4832This observational study investigates the prognostic significance of troponin I in patients undergoing primary percutaneous intervention (pPCI). Sequential cardiac biomarker sampling of the enrolled patients (n = 167) was performed on admission and at 6,12,24 and 48 h. Clinical characteristics, major adverse cardiac and cerebrovascular events (MACCE) (death, reinfarction, stroke and new or worsening heart failure) and left ventricular ejection fraction (LVEF) were noted on admission and 30 day follow-up. A 24-h troponin I level >60 ng/ml predicted MACCE (OR 4.06, p = 0.023; adjusted OR 5.09, p = 0.034) and less than 10% improvement in LVEF on follow-up (OR 2.49, p = 0.007).Thus, in patients undergoing pPCI, 24-h cardiac Troponin I is a good non-invasive surrogate to predict MACCE and improvement in LVEF.Pratik Sudhir Sane, DNBV Manoj, MDRufus Demel, MDS. Vijaykumar, MD, DM ,FNBAjit.S. Mullasari, MD, DNB, DM , FRCPElsevierarticleTroponin IPrimary PCIMACCESurgeryRD1-811Diseases of the circulatory (Cardiovascular) systemRC666-701ENIndian Heart Journal, Vol 73, Iss 6, Pp 737-739 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Troponin I Primary PCI MACCE Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Troponin I Primary PCI MACCE Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701 Pratik Sudhir Sane, DNB V Manoj, MD Rufus Demel, MD S. Vijaykumar, MD, DM ,FNB Ajit.S. Mullasari, MD, DNB, DM , FRCP Prognostic significance of Troponin I in patients undergoing primary percutaneous coronary intervention
description	This observational study investigates the prognostic significance of troponin I in patients undergoing primary percutaneous intervention (pPCI). Sequential cardiac biomarker sampling of the enrolled patients (n = 167) was performed on admission and at 6,12,24 and 48 h. Clinical characteristics, major adverse cardiac and cerebrovascular events (MACCE) (death, reinfarction, stroke and new or worsening heart failure) and left ventricular ejection fraction (LVEF) were noted on admission and 30 day follow-up. A 24-h troponin I level >60 ng/ml predicted MACCE (OR 4.06, p = 0.023; adjusted OR 5.09, p = 0.034) and less than 10% improvement in LVEF on follow-up (OR 2.49, p = 0.007).Thus, in patients undergoing pPCI, 24-h cardiac Troponin I is a good non-invasive surrogate to predict MACCE and improvement in LVEF.
format	article
author	Pratik Sudhir Sane, DNB V Manoj, MD Rufus Demel, MD S. Vijaykumar, MD, DM ,FNB Ajit.S. Mullasari, MD, DNB, DM , FRCP
author_facet	Pratik Sudhir Sane, DNB V Manoj, MD Rufus Demel, MD S. Vijaykumar, MD, DM ,FNB Ajit.S. Mullasari, MD, DNB, DM , FRCP
author_sort	Pratik Sudhir Sane, DNB
title	Prognostic significance of Troponin I in patients undergoing primary percutaneous coronary intervention
title_short	Prognostic significance of Troponin I in patients undergoing primary percutaneous coronary intervention
title_full	Prognostic significance of Troponin I in patients undergoing primary percutaneous coronary intervention
title_fullStr	Prognostic significance of Troponin I in patients undergoing primary percutaneous coronary intervention
title_full_unstemmed	Prognostic significance of Troponin I in patients undergoing primary percutaneous coronary intervention
title_sort	prognostic significance of troponin i in patients undergoing primary percutaneous coronary intervention
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/c3012583a9284945a96ae96ffc1e242f
work_keys_str_mv	AT pratiksudhirsanednb prognosticsignificanceoftroponiniinpatientsundergoingprimarypercutaneouscoronaryintervention AT vmanojmd prognosticsignificanceoftroponiniinpatientsundergoingprimarypercutaneouscoronaryintervention AT rufusdemelmd prognosticsignificanceoftroponiniinpatientsundergoingprimarypercutaneouscoronaryintervention AT svijaykumarmddmfnb prognosticsignificanceoftroponiniinpatientsundergoingprimarypercutaneouscoronaryintervention AT ajitsmullasarimddnbdmfrcp prognosticsignificanceoftroponiniinpatientsundergoingprimarypercutaneouscoronaryintervention
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Prognostic significance of Troponin I in patients undergoing primary percutaneous coronary intervention

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