Oxidative stress and DNA lesions: the role of 8-oxoguanine lesions in Trypanosoma cruzi cell viability.

Oxidative stress and DNA lesions: the role of 8-oxoguanine lesions in Trypanosoma cruzi cell viability.

The main consequence of oxidative stress is the formation of DNA lesions, which can result in genomic instability and lead to cell death. Guanine is the base that is most susceptible to oxidation, due to its low redox potential, and 8-oxoguanine (8-oxoG) is the most common lesion. These characterist...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Pedro H N Aguiar, Carolina Furtado, Bruno M Repolês, Grazielle A Ribeiro, Isabela C Mendes, Eduardo F Peloso, Fernanda R Gadelha, Andrea M Macedo, Glória R Franco, Sérgio D J Pena, Santuza M R Teixeira, Leda Q Vieira, Alessandra A Guarneri, Luciana O Andrade, Carlos R Machado
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
Accès en ligne:https://doaj.org/article/c3030a2328674338ab1d1c9ce0656a09
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/c3030a2328674338ab1d1c9ce0656a09

Documents similaires