Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer
Significant interest in the problem of genetic oncological diseases is due to an increase in the frequency of their detection, existing difficulties of early recognition, disagreements in the clinical and morphological criteria for diagnosis and evaluation of prognostic factors, the absence of gener...
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Scientific Сentre for Family Health and Human Reproduction Problems
2019
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oai:doaj.org-article:c3069bbb60d140bb9744765e1b49557c2021-11-23T06:14:42ZCurrent Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer2541-94202587-959610.29413/ABS.2019-4.2.11https://doaj.org/article/c3069bbb60d140bb9744765e1b49557c2019-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2049https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Significant interest in the problem of genetic oncological diseases is due to an increase in the frequency of their detection, existing difficulties of early recognition, disagreements in the clinical and morphological criteria for diagnosis and evaluation of prognostic factors, the absence of generally accepted standards of treatment and objective assessment of their results.The introduction of new diagnostic technologies into clinical practice (molecular genetic studies, the ability to determine a wide range of hormones and peptides, immunohistochemical determination of general and specific markers, modern methods of topical diagnostics, etc.) allowed us to identify a specific genetic substrate of various types of endocrine organ tumors, previously unknown nosological forms, improve the ability to predict the disease on the preclinical level, to assess their place and importance in the structure of general oncopathology.The issues of terminology, classification, criteria for the degree of malignancy and prognostic factors of hereditary endocrine diseases are particularly relevant. The article presents and analyzes the modern classification and terminological definitions of this group of diseases. The problem of hereditary endocrine tumor diseases and syndromes associated with neuroendocrine tumors (NETs) and multiple endocrine neoplasia syndromes (MEN-syndromes) has been described. In conclusion, the situation with the study of this problem in the Russian Federation is analyzed.S. B. PinskyV. A. BeloborodovV. V. DvornichenkoYu. K. BatoroevV. A. VorobevScientific Сentre for Family Health and Human Reproduction Problemsarticleendocrine organsneuroendocrine tumorsmen-syndromehereditary diseasesScienceQRUActa Biomedica Scientifica, Vol 4, Iss 2, Pp 70-75 (2019) |
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endocrine organs neuroendocrine tumors men-syndrome hereditary diseases Science Q |
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endocrine organs neuroendocrine tumors men-syndrome hereditary diseases Science Q S. B. Pinsky V. A. Beloborodov V. V. Dvornichenko Yu. K. Batoroev V. A. Vorobev Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer |
description |
Significant interest in the problem of genetic oncological diseases is due to an increase in the frequency of their detection, existing difficulties of early recognition, disagreements in the clinical and morphological criteria for diagnosis and evaluation of prognostic factors, the absence of generally accepted standards of treatment and objective assessment of their results.The introduction of new diagnostic technologies into clinical practice (molecular genetic studies, the ability to determine a wide range of hormones and peptides, immunohistochemical determination of general and specific markers, modern methods of topical diagnostics, etc.) allowed us to identify a specific genetic substrate of various types of endocrine organ tumors, previously unknown nosological forms, improve the ability to predict the disease on the preclinical level, to assess their place and importance in the structure of general oncopathology.The issues of terminology, classification, criteria for the degree of malignancy and prognostic factors of hereditary endocrine diseases are particularly relevant. The article presents and analyzes the modern classification and terminological definitions of this group of diseases. The problem of hereditary endocrine tumor diseases and syndromes associated with neuroendocrine tumors (NETs) and multiple endocrine neoplasia syndromes (MEN-syndromes) has been described. In conclusion, the situation with the study of this problem in the Russian Federation is analyzed. |
format |
article |
author |
S. B. Pinsky V. A. Beloborodov V. V. Dvornichenko Yu. K. Batoroev V. A. Vorobev |
author_facet |
S. B. Pinsky V. A. Beloborodov V. V. Dvornichenko Yu. K. Batoroev V. A. Vorobev |
author_sort |
S. B. Pinsky |
title |
Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer |
title_short |
Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer |
title_full |
Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer |
title_fullStr |
Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer |
title_full_unstemmed |
Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer |
title_sort |
current issues in terminology and classification of hereditary disorders at endocrine cancer |
publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
publishDate |
2019 |
url |
https://doaj.org/article/c3069bbb60d140bb9744765e1b49557c |
work_keys_str_mv |
AT sbpinsky currentissuesinterminologyandclassificationofhereditarydisordersatendocrinecancer AT vabeloborodov currentissuesinterminologyandclassificationofhereditarydisordersatendocrinecancer AT vvdvornichenko currentissuesinterminologyandclassificationofhereditarydisordersatendocrinecancer AT yukbatoroev currentissuesinterminologyandclassificationofhereditarydisordersatendocrinecancer AT vavorobev currentissuesinterminologyandclassificationofhereditarydisordersatendocrinecancer |
_version_ |
1718416972963643392 |