Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer

Significant interest in the problem of genetic oncological diseases is due to an increase in the frequency of their detection, existing difficulties of early recognition, disagreements in the clinical and morphological criteria for diagnosis and evaluation of prognostic factors, the absence of gener...

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Autores principales: S. B. Pinsky, V. A. Beloborodov, V. V. Dvornichenko, Yu. K. Batoroev, V. A. Vorobev
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2019
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Acceso en línea:https://doaj.org/article/c3069bbb60d140bb9744765e1b49557c
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spelling oai:doaj.org-article:c3069bbb60d140bb9744765e1b49557c2021-11-23T06:14:42ZCurrent Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer2541-94202587-959610.29413/ABS.2019-4.2.11https://doaj.org/article/c3069bbb60d140bb9744765e1b49557c2019-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2049https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Significant interest in the problem of genetic oncological diseases is due to an increase in the frequency of their detection, existing difficulties of early recognition, disagreements in the clinical and morphological criteria for diagnosis and evaluation of prognostic factors, the absence of generally accepted standards of treatment and objective assessment of their results.The introduction of new diagnostic technologies into clinical practice (molecular genetic studies, the ability to determine a wide range of hormones and peptides, immunohistochemical determination of general and specific markers, modern methods of topical diagnostics, etc.) allowed us to identify a specific genetic substrate of various types of endocrine organ tumors, previously unknown nosological forms, improve the ability to predict the disease on the preclinical level, to assess their place and importance in the structure of general oncopathology.The issues of terminology, classification, criteria for the degree of malignancy and prognostic factors of hereditary endocrine diseases are particularly relevant. The article presents and analyzes the modern classification and terminological definitions of this group of diseases. The problem of hereditary endocrine tumor diseases and syndromes associated with neuroendocrine tumors (NETs) and multiple endocrine neoplasia syndromes (MEN-syndromes) has been described. In conclusion, the situation with the study of this problem in the Russian Federation is analyzed.S. B. PinskyV. A. BeloborodovV. V. DvornichenkoYu. K. BatoroevV. A. VorobevScientific Сentre for Family Health and Human Reproduction Problemsarticleendocrine organsneuroendocrine tumorsmen-syndromehereditary diseasesScienceQRUActa Biomedica Scientifica, Vol 4, Iss 2, Pp 70-75 (2019)
institution DOAJ
collection DOAJ
language RU
topic endocrine organs
neuroendocrine tumors
men-syndrome
hereditary diseases
Science
Q
spellingShingle endocrine organs
neuroendocrine tumors
men-syndrome
hereditary diseases
Science
Q
S. B. Pinsky
V. A. Beloborodov
V. V. Dvornichenko
Yu. K. Batoroev
V. A. Vorobev
Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer
description Significant interest in the problem of genetic oncological diseases is due to an increase in the frequency of their detection, existing difficulties of early recognition, disagreements in the clinical and morphological criteria for diagnosis and evaluation of prognostic factors, the absence of generally accepted standards of treatment and objective assessment of their results.The introduction of new diagnostic technologies into clinical practice (molecular genetic studies, the ability to determine a wide range of hormones and peptides, immunohistochemical determination of general and specific markers, modern methods of topical diagnostics, etc.) allowed us to identify a specific genetic substrate of various types of endocrine organ tumors, previously unknown nosological forms, improve the ability to predict the disease on the preclinical level, to assess their place and importance in the structure of general oncopathology.The issues of terminology, classification, criteria for the degree of malignancy and prognostic factors of hereditary endocrine diseases are particularly relevant. The article presents and analyzes the modern classification and terminological definitions of this group of diseases. The problem of hereditary endocrine tumor diseases and syndromes associated with neuroendocrine tumors (NETs) and multiple endocrine neoplasia syndromes (MEN-syndromes) has been described. In conclusion, the situation with the study of this problem in the Russian Federation is analyzed.
format article
author S. B. Pinsky
V. A. Beloborodov
V. V. Dvornichenko
Yu. K. Batoroev
V. A. Vorobev
author_facet S. B. Pinsky
V. A. Beloborodov
V. V. Dvornichenko
Yu. K. Batoroev
V. A. Vorobev
author_sort S. B. Pinsky
title Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer
title_short Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer
title_full Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer
title_fullStr Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer
title_full_unstemmed Current Issues in Terminology and Classification of Hereditary Disorders at Endocrine Cancer
title_sort current issues in terminology and classification of hereditary disorders at endocrine cancer
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2019
url https://doaj.org/article/c3069bbb60d140bb9744765e1b49557c
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AT vabeloborodov currentissuesinterminologyandclassificationofhereditarydisordersatendocrinecancer
AT vvdvornichenko currentissuesinterminologyandclassificationofhereditarydisordersatendocrinecancer
AT yukbatoroev currentissuesinterminologyandclassificationofhereditarydisordersatendocrinecancer
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