Testing assembly strategies of Francisella tularensis genomes to infer an evolutionary conservation analysis of genomic structures

Abstract Background We benchmarked sequencing technology and assembly strategies for short-read, long-read, and hybrid assemblers in respect to correctness, contiguity, and completeness of assemblies in genomes of Francisella tularensis. Benchmarking allowed in-depth analyses of genomic structures o...

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Autores principales:	Kerstin Neubert, Eric Zuchantke, Robert Maximilian Leidenfrost, Roebbe Wuenschiers, Josephine Grützke, Burkhard Malorny, Holger Brendebach, Sascha Al Dahouk, Timo Homeier, Helmut Hotzel, Knut Reinert, Herbert Tomaso, Anne Busch
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Francisella pathogenicity island Insertion sequences High-throughput sequencing Short-read assembly Hybrid assembly Ion Torrent’s ion S5 Biotechnology TP248.13-248.65 Genetics QH426-470
Acceso en línea:	https://doaj.org/article/c30de5e7596e46d2b4a57628b591e229
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Testing assembly strategies of Francisella tularensis genomes to infer an evolutionary conservation analysis of genomic structures

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