Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub
Summary: Functional tags are ubiquitous in cell biology, and for studies of one chromosomal locus, the centromere, tags have been remarkably useful. The centromere directs chromosome inheritance at cell division. The location of the centromere is defined by a histone H3 variant, CENP-A. The regulati...
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Autores principales: | , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c312cc62e4fe4719a23103d6d0993732 |
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