Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population

Blood metabolites are influenced by a combination of genetic and environmental factors. Here, Yousri and colleagues perform a whole-exome sequencing study in combination with a metabolomics analysis to identify metabolic quantitative trait loci in a Middle Eastern population.

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Autores principales: Noha A. Yousri, Khalid A. Fakhro, Amal Robay, Juan L. Rodriguez-Flores, Robert P. Mohney, Hassina Zeriri, Tala Odeh, Sara Abdul Kader, Eman K. Aldous, Gaurav Thareja, Manish Kumar, Alya Al-Shakaki, Omar M. Chidiac, Yasmin A. Mohamoud, Jason G. Mezey, Joel A. Malek, Ronald G. Crystal, Karsten Suhre
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c31de4379d5747af8230fd50df05087b
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spelling oai:doaj.org-article:c31de4379d5747af8230fd50df05087b2021-12-02T14:39:05ZWhole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population10.1038/s41467-017-01972-92041-1723https://doaj.org/article/c31de4379d5747af8230fd50df05087b2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01972-9https://doaj.org/toc/2041-1723Blood metabolites are influenced by a combination of genetic and environmental factors. Here, Yousri and colleagues perform a whole-exome sequencing study in combination with a metabolomics analysis to identify metabolic quantitative trait loci in a Middle Eastern population.Noha A. YousriKhalid A. FakhroAmal RobayJuan L. Rodriguez-FloresRobert P. MohneyHassina ZeririTala OdehSara Abdul KaderEman K. AldousGaurav TharejaManish KumarAlya Al-ShakakiOmar M. ChidiacYasmin A. MohamoudJason G. MezeyJoel A. MalekRonald G. CrystalKarsten SuhreNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Noha A. Yousri
Khalid A. Fakhro
Amal Robay
Juan L. Rodriguez-Flores
Robert P. Mohney
Hassina Zeriri
Tala Odeh
Sara Abdul Kader
Eman K. Aldous
Gaurav Thareja
Manish Kumar
Alya Al-Shakaki
Omar M. Chidiac
Yasmin A. Mohamoud
Jason G. Mezey
Joel A. Malek
Ronald G. Crystal
Karsten Suhre
Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population
description Blood metabolites are influenced by a combination of genetic and environmental factors. Here, Yousri and colleagues perform a whole-exome sequencing study in combination with a metabolomics analysis to identify metabolic quantitative trait loci in a Middle Eastern population.
format article
author Noha A. Yousri
Khalid A. Fakhro
Amal Robay
Juan L. Rodriguez-Flores
Robert P. Mohney
Hassina Zeriri
Tala Odeh
Sara Abdul Kader
Eman K. Aldous
Gaurav Thareja
Manish Kumar
Alya Al-Shakaki
Omar M. Chidiac
Yasmin A. Mohamoud
Jason G. Mezey
Joel A. Malek
Ronald G. Crystal
Karsten Suhre
author_facet Noha A. Yousri
Khalid A. Fakhro
Amal Robay
Juan L. Rodriguez-Flores
Robert P. Mohney
Hassina Zeriri
Tala Odeh
Sara Abdul Kader
Eman K. Aldous
Gaurav Thareja
Manish Kumar
Alya Al-Shakaki
Omar M. Chidiac
Yasmin A. Mohamoud
Jason G. Mezey
Joel A. Malek
Ronald G. Crystal
Karsten Suhre
author_sort Noha A. Yousri
title Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population
title_short Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population
title_full Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population
title_fullStr Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population
title_full_unstemmed Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population
title_sort whole-exome sequencing identifies common and rare variant metabolic qtls in a middle eastern population
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/c31de4379d5747af8230fd50df05087b
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