Loss of Dependence on Continued Expression of the Human Papillomavirus 16 E7 Oncogene in Cervical Cancers and Precancerous Lesions Arising in Fanconi Anemia Pathway-Deficient Mice

ABSTRACT   Fanconi anemia (FA) is a rare genetic disorder caused by defects in DNA damage repair. FA patients often develop squamous cell carcinoma (SCC) at sites where high-risk human papillomaviruses (HPVs) are known to cause cancer, including the cervix. However, SCCs found in human FA patients a...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Soyeong Park, Jung Wook Park, Henry C. Pitot, Paul F. Lambert
Format: article
Langue:EN
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://doaj.org/article/c31f14d93ff74696994b0fb273811e06
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!