Comparison Of Accelerated Partial Breast Radiation Therapy And External Beam Radiation Therapy By Treatment Planning Indices

Peyman Hejazi,1 Maede Jafari Tirtash,2 Alireza Khoshbin Khoshnazar3 1Department of Medical Physics, Semnan University of Medical Sciences, Semnan, Iran; 2Department of Radiotherapy, Mirdamad Oncology and Radiotherapy Center, Gorgan, Iran; 3Department of Biochemistry and Medical Physics, Faculty of M...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hejazi P, Tirtash MJ, Khoshnazar AK
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	partial radiation therapy external beam radiation therapy breast cancer Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/c3251811da5d42c6b12950cb54f312dd
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c3251811da5d42c6b12950cb54f312dd
record_format	dspace
spelling	oai:doaj.org-article:c3251811da5d42c6b12950cb54f312dd2021-12-02T07:50:02ZComparison Of Accelerated Partial Breast Radiation Therapy And External Beam Radiation Therapy By Treatment Planning Indices1179-1314https://doaj.org/article/c3251811da5d42c6b12950cb54f312dd2019-11-01T00:00:00Zhttps://www.dovepress.com/comparison-of-accelerated-partial-breast-radiation-therapy-and-externa-peer-reviewed-article-BCTThttps://doaj.org/toc/1179-1314Peyman Hejazi,1 Maede Jafari Tirtash,2 Alireza Khoshbin Khoshnazar3 1Department of Medical Physics, Semnan University of Medical Sciences, Semnan, Iran; 2Department of Radiotherapy, Mirdamad Oncology and Radiotherapy Center, Gorgan, Iran; 3Department of Biochemistry and Medical Physics, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, IranCorrespondence: Alireza Khoshbin KhoshnazarDepartment of Biochemistry and Medical Physics, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, IranTel +98-9113773145Email akhoshbin@yahoo.comBackground: Accelerated partial breast irradiation (APBI) is a method in which just bed of lumpectomy with a margin of 1–2 cm is irradiated. Regarding advantages of APBI to whole-brain radiation therapy (WBRT) and limitations for performing other techniques, we compare external beam radiation therapy (EBRT) with three-dimensional conformal radiation therapy (3DCRT), as a type of APBI technique.Methods: Dosimetric parameters including uniformity index (UI), conformity index (CI), and homogeneity index (HI) beside heart and lung doses were assessed and compared in two techniques. CT images of 24 patients with left-sided breast cancer after lumpectomy were selected. Patients were categorized into three groups based on the volume of breast, respectively, ≤ 1000 cc, 1000–1500 cc, and ≥ 1500 cc. CI, HI, UI and DVH were calculated by DosiSoftIsogray treatment planning software.Results: Results show the value of UI in APBI method is more than EBRT method significantly (p=0.004). Moreover, that CI in APBI method was more than EBRT (p=0.0000) and nearer to 1. There was no significant difference between HI values between APBI and EBRT methods. As the volume of breast gets bigger, HI values rise, meaning worse homogeneity.Conclusion: APBI method may be a good method for minimizing side effect and minimizing treatment periods.Keywords: partial radiation therapy, external beam radiation therapy, breast cancerHejazi PTirtash MJKhoshnazar AKDove Medical Pressarticlepartial radiation therapyexternal beam radiation therapybreast cancerNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBreast Cancer: Targets and Therapy, Vol Volume 11, Pp 303-307 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	partial radiation therapy external beam radiation therapy breast cancer Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	partial radiation therapy external beam radiation therapy breast cancer Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Hejazi P Tirtash MJ Khoshnazar AK Comparison Of Accelerated Partial Breast Radiation Therapy And External Beam Radiation Therapy By Treatment Planning Indices
description	Peyman Hejazi,1 Maede Jafari Tirtash,2 Alireza Khoshbin Khoshnazar3 1Department of Medical Physics, Semnan University of Medical Sciences, Semnan, Iran; 2Department of Radiotherapy, Mirdamad Oncology and Radiotherapy Center, Gorgan, Iran; 3Department of Biochemistry and Medical Physics, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, IranCorrespondence: Alireza Khoshbin KhoshnazarDepartment of Biochemistry and Medical Physics, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, IranTel +98-9113773145Email akhoshbin@yahoo.comBackground: Accelerated partial breast irradiation (APBI) is a method in which just bed of lumpectomy with a margin of 1–2 cm is irradiated. Regarding advantages of APBI to whole-brain radiation therapy (WBRT) and limitations for performing other techniques, we compare external beam radiation therapy (EBRT) with three-dimensional conformal radiation therapy (3DCRT), as a type of APBI technique.Methods: Dosimetric parameters including uniformity index (UI), conformity index (CI), and homogeneity index (HI) beside heart and lung doses were assessed and compared in two techniques. CT images of 24 patients with left-sided breast cancer after lumpectomy were selected. Patients were categorized into three groups based on the volume of breast, respectively, ≤ 1000 cc, 1000–1500 cc, and ≥ 1500 cc. CI, HI, UI and DVH were calculated by DosiSoftIsogray treatment planning software.Results: Results show the value of UI in APBI method is more than EBRT method significantly (p=0.004). Moreover, that CI in APBI method was more than EBRT (p=0.0000) and nearer to 1. There was no significant difference between HI values between APBI and EBRT methods. As the volume of breast gets bigger, HI values rise, meaning worse homogeneity.Conclusion: APBI method may be a good method for minimizing side effect and minimizing treatment periods.Keywords: partial radiation therapy, external beam radiation therapy, breast cancer
format	article
author	Hejazi P Tirtash MJ Khoshnazar AK
author_facet	Hejazi P Tirtash MJ Khoshnazar AK
author_sort	Hejazi P
title	Comparison Of Accelerated Partial Breast Radiation Therapy And External Beam Radiation Therapy By Treatment Planning Indices
title_short	Comparison Of Accelerated Partial Breast Radiation Therapy And External Beam Radiation Therapy By Treatment Planning Indices
title_full	Comparison Of Accelerated Partial Breast Radiation Therapy And External Beam Radiation Therapy By Treatment Planning Indices
title_fullStr	Comparison Of Accelerated Partial Breast Radiation Therapy And External Beam Radiation Therapy By Treatment Planning Indices
title_full_unstemmed	Comparison Of Accelerated Partial Breast Radiation Therapy And External Beam Radiation Therapy By Treatment Planning Indices
title_sort	comparison of accelerated partial breast radiation therapy and external beam radiation therapy by treatment planning indices
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/c3251811da5d42c6b12950cb54f312dd
work_keys_str_mv	AT hejazip comparisonofacceleratedpartialbreastradiationtherapyandexternalbeamradiationtherapybytreatmentplanningindices AT tirtashmj comparisonofacceleratedpartialbreastradiationtherapyandexternalbeamradiationtherapybytreatmentplanningindices AT khoshnazarak comparisonofacceleratedpartialbreastradiationtherapyandexternalbeamradiationtherapybytreatmentplanningindices
_version_	1718399183388409856

Comparison Of Accelerated Partial Breast Radiation Therapy And External Beam Radiation Therapy By Treatment Planning Indices

Ejemplares similares