Mapping the sensing spots of aerolysin for single oligonucleotides analysis

Nanopores are an emerging powerful single-molecule method of DNA sequencing. Here the authors map the structure of aerolysin for use as a nanopore and show detection of modified and unmodified nucleobases.

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Autores principales: Chan Cao, Meng-Yin Li, Nuria Cirauqui, Ya-Qian Wang, Matteo Dal Peraro, He Tian, Yi-Tao Long
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c327e0aef98b4474928cf914bf232de3
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spelling oai:doaj.org-article:c327e0aef98b4474928cf914bf232de32021-12-02T16:50:06ZMapping the sensing spots of aerolysin for single oligonucleotides analysis10.1038/s41467-018-05108-52041-1723https://doaj.org/article/c327e0aef98b4474928cf914bf232de32018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05108-5https://doaj.org/toc/2041-1723Nanopores are an emerging powerful single-molecule method of DNA sequencing. Here the authors map the structure of aerolysin for use as a nanopore and show detection of modified and unmodified nucleobases.Chan CaoMeng-Yin LiNuria CirauquiYa-Qian WangMatteo Dal PeraroHe TianYi-Tao LongNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chan Cao
Meng-Yin Li
Nuria Cirauqui
Ya-Qian Wang
Matteo Dal Peraro
He Tian
Yi-Tao Long
Mapping the sensing spots of aerolysin for single oligonucleotides analysis
description Nanopores are an emerging powerful single-molecule method of DNA sequencing. Here the authors map the structure of aerolysin for use as a nanopore and show detection of modified and unmodified nucleobases.
format article
author Chan Cao
Meng-Yin Li
Nuria Cirauqui
Ya-Qian Wang
Matteo Dal Peraro
He Tian
Yi-Tao Long
author_facet Chan Cao
Meng-Yin Li
Nuria Cirauqui
Ya-Qian Wang
Matteo Dal Peraro
He Tian
Yi-Tao Long
author_sort Chan Cao
title Mapping the sensing spots of aerolysin for single oligonucleotides analysis
title_short Mapping the sensing spots of aerolysin for single oligonucleotides analysis
title_full Mapping the sensing spots of aerolysin for single oligonucleotides analysis
title_fullStr Mapping the sensing spots of aerolysin for single oligonucleotides analysis
title_full_unstemmed Mapping the sensing spots of aerolysin for single oligonucleotides analysis
title_sort mapping the sensing spots of aerolysin for single oligonucleotides analysis
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/c327e0aef98b4474928cf914bf232de3
work_keys_str_mv AT chancao mappingthesensingspotsofaerolysinforsingleoligonucleotidesanalysis
AT mengyinli mappingthesensingspotsofaerolysinforsingleoligonucleotidesanalysis
AT nuriacirauqui mappingthesensingspotsofaerolysinforsingleoligonucleotidesanalysis
AT yaqianwang mappingthesensingspotsofaerolysinforsingleoligonucleotidesanalysis
AT matteodalperaro mappingthesensingspotsofaerolysinforsingleoligonucleotidesanalysis
AT hetian mappingthesensingspotsofaerolysinforsingleoligonucleotidesanalysis
AT yitaolong mappingthesensingspotsofaerolysinforsingleoligonucleotidesanalysis
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