Relationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder

Haruka Yamamoto,1 Hideto Tsuchida,1 Takashi Nakamae,1 Seiji Nishida,1 Yuki Sakai,1 Akihito Fujimori,1 Jin Narumoto,1 Yoshihisa Wada,1 Takafumi Yoshida,2 Chiaki Taga,3 Kenji Fukui11Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan; 2K...

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Autores principales:	Yamamoto H, Tsuchida H, Nakamae T, Nishida S, Sakai Y, Fujimori A, Narumoto J, Wada Y, Yoshida T, Taga C, Fukui K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/c3439b5751e449a39485d6d577b0e844
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spelling	oai:doaj.org-article:c3439b5751e449a39485d6d577b0e8442021-12-02T06:07:46ZRelationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder1176-63281178-2021https://doaj.org/article/c3439b5751e449a39485d6d577b0e8442012-12-01T00:00:00Zhttp://www.dovepress.com/relationship-between-severity-of-obsessive-compulsive-symptoms-and-sch-a11699https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Haruka Yamamoto,1 Hideto Tsuchida,1 Takashi Nakamae,1 Seiji Nishida,1 Yuki Sakai,1 Akihito Fujimori,1 Jin Narumoto,1 Yoshihisa Wada,1 Takafumi Yoshida,2 Chiaki Taga,3 Kenji Fukui11Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan; 2Kyoto Cognitive Behavior Therapy Counseling Room, Kyoto, Japan; 3Department of Psychiatry, Kyoto Second Red Cross Hospital, Kyoto, JapanPurpose: Obsessive-compulsive disorder (OCD) patients exhibit a noninhibition response pattern very similar to that observed in schizotypy patients in cognitive tasks. It has been suggested that the reduced cognitive inhibition observed in both schizotypy and OCD may result in the frequent entry into awareness of unacceptable urges and intrusive thoughts. The aim of this study was to investigate the relationship between the severity of obsession or compulsion and schizotypy in OCD.Patients and methods: Sixty subjects (25 males and 35 females) who were OCD outpatients in the University Hospital at the Kyoto Prefectural University of Medicine during the period 2008&ndash;2010 were enrolled in the study. Assessments of these patients were made using the Yale&ndash;Brown Obsessive Compulsive Scale (Y-BOCS), the Schizotypal Personality Questionnaire (SPQ), the Hamilton Depression Rating Scale (HAM-D), and the Hamilton Anxiety Rating Scale (HAM-A). The Pearson correlation coefficients between Y-BOCS and SPQ scores were calculated. Furthermore, hierarchical multiple linear regression analyses were conducted to assess whether schizotypy predicted the severity of obsession and compulsion.Results: By calculating the Pearson correlation coefficient, it was found that the Y-BOCS obsession score, not the Y-BOCS compulsion score, was correlated with the SPQ total score. Results of the hierarchical multiple linear regression analysis showed that SPQ total score was a significant predictor of the Y-BOCS obsession score, after accounting for control variables (ie, HAM-D and HAM-A).Conclusion: Results of this study showed that the Y-BOCS obsession score, not the Y-BOCS compulsion score, was correlated with the SPQ total score. This finding suggests that OCD patients with an elevated SPQ total score experience a reduction of cognitive inhibition, resulting in the frequent entry into obsession. Future longitudinal studies are recommended to clarify the effect of schizotypy on the clinical course of OCD. Keywords: Y-BOCS, obsession, compulsion, severityYamamoto HTsuchida HNakamae TNishida SSakai YFujimori ANarumoto JWada YYoshida TTaga CFukui KDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2012, Iss default, Pp 579-583 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Yamamoto H Tsuchida H Nakamae T Nishida S Sakai Y Fujimori A Narumoto J Wada Y Yoshida T Taga C Fukui K Relationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder
description	Haruka Yamamoto,1 Hideto Tsuchida,1 Takashi Nakamae,1 Seiji Nishida,1 Yuki Sakai,1 Akihito Fujimori,1 Jin Narumoto,1 Yoshihisa Wada,1 Takafumi Yoshida,2 Chiaki Taga,3 Kenji Fukui11Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan; 2Kyoto Cognitive Behavior Therapy Counseling Room, Kyoto, Japan; 3Department of Psychiatry, Kyoto Second Red Cross Hospital, Kyoto, JapanPurpose: Obsessive-compulsive disorder (OCD) patients exhibit a noninhibition response pattern very similar to that observed in schizotypy patients in cognitive tasks. It has been suggested that the reduced cognitive inhibition observed in both schizotypy and OCD may result in the frequent entry into awareness of unacceptable urges and intrusive thoughts. The aim of this study was to investigate the relationship between the severity of obsession or compulsion and schizotypy in OCD.Patients and methods: Sixty subjects (25 males and 35 females) who were OCD outpatients in the University Hospital at the Kyoto Prefectural University of Medicine during the period 2008&ndash;2010 were enrolled in the study. Assessments of these patients were made using the Yale&ndash;Brown Obsessive Compulsive Scale (Y-BOCS), the Schizotypal Personality Questionnaire (SPQ), the Hamilton Depression Rating Scale (HAM-D), and the Hamilton Anxiety Rating Scale (HAM-A). The Pearson correlation coefficients between Y-BOCS and SPQ scores were calculated. Furthermore, hierarchical multiple linear regression analyses were conducted to assess whether schizotypy predicted the severity of obsession and compulsion.Results: By calculating the Pearson correlation coefficient, it was found that the Y-BOCS obsession score, not the Y-BOCS compulsion score, was correlated with the SPQ total score. Results of the hierarchical multiple linear regression analysis showed that SPQ total score was a significant predictor of the Y-BOCS obsession score, after accounting for control variables (ie, HAM-D and HAM-A).Conclusion: Results of this study showed that the Y-BOCS obsession score, not the Y-BOCS compulsion score, was correlated with the SPQ total score. This finding suggests that OCD patients with an elevated SPQ total score experience a reduction of cognitive inhibition, resulting in the frequent entry into obsession. Future longitudinal studies are recommended to clarify the effect of schizotypy on the clinical course of OCD. Keywords: Y-BOCS, obsession, compulsion, severity
format	article
author	Yamamoto H Tsuchida H Nakamae T Nishida S Sakai Y Fujimori A Narumoto J Wada Y Yoshida T Taga C Fukui K
author_facet	Yamamoto H Tsuchida H Nakamae T Nishida S Sakai Y Fujimori A Narumoto J Wada Y Yoshida T Taga C Fukui K
author_sort	Yamamoto H
title	Relationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder
title_short	Relationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder
title_full	Relationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder
title_fullStr	Relationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder
title_full_unstemmed	Relationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder
title_sort	relationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/c3439b5751e449a39485d6d577b0e844
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Relationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder

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