The DNA methylation landscape of giant viruses

DNA methylation is an epigenetic marker in all domains of life. Here, Jeudy et al., using single-molecule realtime sequencing, determine DNA methylation patterns in giant viruses and evolutionary analysis of virus encoded DNA methyltransferases suggests that they affect viral fitness.

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Autores principales: Sandra Jeudy, Sofia Rigou, Jean-Marie Alempic, Jean-Michel Claverie, Chantal Abergel, Matthieu Legendre
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c3452ec6a6264e06b8f9bcf1bb5267b2
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Sumario:DNA methylation is an epigenetic marker in all domains of life. Here, Jeudy et al., using single-molecule realtime sequencing, determine DNA methylation patterns in giant viruses and evolutionary analysis of virus encoded DNA methyltransferases suggests that they affect viral fitness.