Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination

Myelination patterns of different neurons in grey matter have not been fully defined. Here, the authors show that axon diameter and neuronal identity influence myelination patterns in the intact mouse somatosensory cortex. In vivo imaging revealed that remyelination altered myelin patterns but resto...

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Autores principales:	Cody L. Call, Dwight E. Bergles
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c346bd3222c5430cb2eb4580c03d6065
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spelling	oai:doaj.org-article:c346bd3222c5430cb2eb4580c03d60652021-12-02T18:49:35ZCortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination10.1038/s41467-021-25035-22041-1723https://doaj.org/article/c346bd3222c5430cb2eb4580c03d60652021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25035-2https://doaj.org/toc/2041-1723Myelination patterns of different neurons in grey matter have not been fully defined. Here, the authors show that axon diameter and neuronal identity influence myelination patterns in the intact mouse somatosensory cortex. In vivo imaging revealed that remyelination altered myelin patterns but restored overall myelin content on distinct neuron subtypes.Cody L. CallDwight E. BerglesNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cody L. Call Dwight E. Bergles Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination
description	Myelination patterns of different neurons in grey matter have not been fully defined. Here, the authors show that axon diameter and neuronal identity influence myelination patterns in the intact mouse somatosensory cortex. In vivo imaging revealed that remyelination altered myelin patterns but restored overall myelin content on distinct neuron subtypes.
format	article
author	Cody L. Call Dwight E. Bergles
author_facet	Cody L. Call Dwight E. Bergles
author_sort	Cody L. Call
title	Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination
title_short	Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination
title_full	Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination
title_fullStr	Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination
title_full_unstemmed	Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination
title_sort	cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c346bd3222c5430cb2eb4580c03d6065
work_keys_str_mv	AT codylcall corticalneuronsexhibitdiversemyelinationpatternsthatscalebetweenmousebrainregionsandregenerateafterdemyelination AT dwightebergles corticalneuronsexhibitdiversemyelinationpatternsthatscalebetweenmousebrainregionsandregenerateafterdemyelination
_version_	1718377589049917440

Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination

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