A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patients
Abstract Studies have shown that tumor microenvironment (TME) might affect drug sensitivity and the classification of colorectal cancer (CRC). Using TME-specific gene signature to identify CRC subtypes with distinctive clinical relevance has not yet been tested. A total of 18 “bulk” RNA-seq datasets...
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Autores principales: | Xiaoqiang Zhu, Xianglong Tian, Linhua Ji, Xinyu Zhang, Yingying Cao, Chaoqin Shen, Ye Hu, Jason W. H. Wong, Jing-Yuan Fang, Jie Hong, Haoyan Chen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c347240ed3e94a05aee507283d7dc3f6 |
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