mSphere of Influence: the Value of Simplicity in Experiments and Solidarity among Lab Members

ABSTRACT Nicholas Wallace studies how human papillomaviruses cause cancer throughout the genital and oropharyngeal tracts as well as in the skin. These viruses inhibit host DNA repair to promote their life style and in doing increase the risk of oncogenic mutations. In this mSphere of Influence arti...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Nicholas A. Wallace
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://doaj.org/article/c347e1d52e484eecb9bc2393a30df554
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:c347e1d52e484eecb9bc2393a30df554
record_format dspace
spelling oai:doaj.org-article:c347e1d52e484eecb9bc2393a30df5542021-11-15T15:22:20ZmSphere of Influence: the Value of Simplicity in Experiments and Solidarity among Lab Members10.1128/mSphere.00172-192379-5042https://doaj.org/article/c347e1d52e484eecb9bc2393a30df5542019-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00172-19https://doaj.org/toc/2379-5042ABSTRACT Nicholas Wallace studies how human papillomaviruses cause cancer throughout the genital and oropharyngeal tracts as well as in the skin. These viruses inhibit host DNA repair to promote their life style and in doing increase the risk of oncogenic mutations. In this mSphere of Influence article, he reflects on how two papers influenced him. “Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation” by C. A. Moody and L. Laimins (PLoS Pathog 5:e10000605, 2009, https://doi.org/10.1371/journal.ppat.1000605) reminded him of the power of straightforward approaches, while “Forty-Five Years of Cell-Cycle Genetics” by B. Reid et al. (B. J. Reid, J. G. Culotti, R. S. Nash, and J. R. Pringle, Mol Biol Cell 26:4307–4312, 2015, https://doi.org/10.1091/mbc.E14-10-1484) gave him the inspiration for his lab management style.Nicholas A. WallaceAmerican Society for MicrobiologyarticleDNA repaircervical cancerhuman papillomavirusMicrobiologyQR1-502ENmSphere, Vol 4, Iss 3 (2019)
institution DOAJ
collection DOAJ
language EN
topic DNA repair
cervical cancer
human papillomavirus
Microbiology
QR1-502
spellingShingle DNA repair
cervical cancer
human papillomavirus
Microbiology
QR1-502
Nicholas A. Wallace
mSphere of Influence: the Value of Simplicity in Experiments and Solidarity among Lab Members
description ABSTRACT Nicholas Wallace studies how human papillomaviruses cause cancer throughout the genital and oropharyngeal tracts as well as in the skin. These viruses inhibit host DNA repair to promote their life style and in doing increase the risk of oncogenic mutations. In this mSphere of Influence article, he reflects on how two papers influenced him. “Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation” by C. A. Moody and L. Laimins (PLoS Pathog 5:e10000605, 2009, https://doi.org/10.1371/journal.ppat.1000605) reminded him of the power of straightforward approaches, while “Forty-Five Years of Cell-Cycle Genetics” by B. Reid et al. (B. J. Reid, J. G. Culotti, R. S. Nash, and J. R. Pringle, Mol Biol Cell 26:4307–4312, 2015, https://doi.org/10.1091/mbc.E14-10-1484) gave him the inspiration for his lab management style.
format article
author Nicholas A. Wallace
author_facet Nicholas A. Wallace
author_sort Nicholas A. Wallace
title mSphere of Influence: the Value of Simplicity in Experiments and Solidarity among Lab Members
title_short mSphere of Influence: the Value of Simplicity in Experiments and Solidarity among Lab Members
title_full mSphere of Influence: the Value of Simplicity in Experiments and Solidarity among Lab Members
title_fullStr mSphere of Influence: the Value of Simplicity in Experiments and Solidarity among Lab Members
title_full_unstemmed mSphere of Influence: the Value of Simplicity in Experiments and Solidarity among Lab Members
title_sort msphere of influence: the value of simplicity in experiments and solidarity among lab members
publisher American Society for Microbiology
publishDate 2019
url https://doaj.org/article/c347e1d52e484eecb9bc2393a30df554
work_keys_str_mv AT nicholasawallace msphereofinfluencethevalueofsimplicityinexperimentsandsolidarityamonglabmembers
_version_ 1718428031682347008