Phenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide

Clarification of the interactions between engineered nanomaterials and multiple generations of insects is crucial to understanding the impact of nanotechnology on the environment and agriculture, particularly in toxicity management, pest management and genetic engineering. To date, there has been ve...

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Autores principales:	Xiuping Wang, Tiantao Zhang, Haicui Xie, Zhenying Wang, Dapeng Jing, Kanglai He, Xiaoduo Gao
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Graphene oxide Asian corn borer Promote the growth Trypsin-like serine protease Environmental pollution TD172-193.5 Environmental sciences GE1-350
Acceso en línea:	https://doaj.org/article/c3501a7500984eeda5f05dd7000c7847
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spelling	oai:doaj.org-article:c3501a7500984eeda5f05dd7000c78472021-11-22T04:16:47ZPhenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide0147-651310.1016/j.ecoenv.2021.113008https://doaj.org/article/c3501a7500984eeda5f05dd7000c78472021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S0147651321011209https://doaj.org/toc/0147-6513Clarification of the interactions between engineered nanomaterials and multiple generations of insects is crucial to understanding the impact of nanotechnology on the environment and agriculture, particularly in toxicity management, pest management and genetic engineering. To date, there has been very limited information about nanoparticle-insect interactions at the genetic and proteomic levels. Here, we examined the phenotypic responses and potential mechanism of a lepidopteran insect Asian corn borer (ACB) to graphene oxide (GO). It was demonstrated that GO could significantly promote the growth of ACB. The transcriptomic and proteomic results consistently verified that GO might activate trypsin-like serine protease, glutathione S-transferase, heat shock protein and glycosyltransferase to further influence the development of ACB. RNA interference results indicated that the trypsin gene was one of the critical genes to accelerate the growth of ACB fed with GO diet. Moreover, physiological analysis showed potential alterations of the expression levels of genes and proteins, and more cholesterol (CE), triacylglycerides (TG) and lipids were accumulated in GO-exposed ACB. Our findings may help to reveal the phenotypic, physiological and genetic responses of insects under exposure to nanomaterials and to assess the environmental risks of other nanomaterials.Xiuping WangTiantao ZhangHaicui XieZhenying WangDapeng JingKanglai HeXiaoduo GaoElsevierarticleGraphene oxideAsian corn borerPromote the growthTrypsin-like serine proteaseEnvironmental pollutionTD172-193.5Environmental sciencesGE1-350ENEcotoxicology and Environmental Safety, Vol 228, Iss , Pp 113008- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Graphene oxide Asian corn borer Promote the growth Trypsin-like serine protease Environmental pollution TD172-193.5 Environmental sciences GE1-350
spellingShingle	Graphene oxide Asian corn borer Promote the growth Trypsin-like serine protease Environmental pollution TD172-193.5 Environmental sciences GE1-350 Xiuping Wang Tiantao Zhang Haicui Xie Zhenying Wang Dapeng Jing Kanglai He Xiaoduo Gao Phenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide
description	Clarification of the interactions between engineered nanomaterials and multiple generations of insects is crucial to understanding the impact of nanotechnology on the environment and agriculture, particularly in toxicity management, pest management and genetic engineering. To date, there has been very limited information about nanoparticle-insect interactions at the genetic and proteomic levels. Here, we examined the phenotypic responses and potential mechanism of a lepidopteran insect Asian corn borer (ACB) to graphene oxide (GO). It was demonstrated that GO could significantly promote the growth of ACB. The transcriptomic and proteomic results consistently verified that GO might activate trypsin-like serine protease, glutathione S-transferase, heat shock protein and glycosyltransferase to further influence the development of ACB. RNA interference results indicated that the trypsin gene was one of the critical genes to accelerate the growth of ACB fed with GO diet. Moreover, physiological analysis showed potential alterations of the expression levels of genes and proteins, and more cholesterol (CE), triacylglycerides (TG) and lipids were accumulated in GO-exposed ACB. Our findings may help to reveal the phenotypic, physiological and genetic responses of insects under exposure to nanomaterials and to assess the environmental risks of other nanomaterials.
format	article
author	Xiuping Wang Tiantao Zhang Haicui Xie Zhenying Wang Dapeng Jing Kanglai He Xiaoduo Gao
author_facet	Xiuping Wang Tiantao Zhang Haicui Xie Zhenying Wang Dapeng Jing Kanglai He Xiaoduo Gao
author_sort	Xiuping Wang
title	Phenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide
title_short	Phenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide
title_full	Phenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide
title_fullStr	Phenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide
title_full_unstemmed	Phenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide
title_sort	phenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/c3501a7500984eeda5f05dd7000c7847
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Phenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide

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