Objective Quantification of Image Quality and Optical Scatter Before and After Nd:YAG Capsulotomy Using a Double-Pass Technique

Abu-Bakar Zafar,1 Richard C Chu,2 Miranda N Bishara,3 Mujtaba A Qazi,4,5 Ashraf M Mahmoud,6 Jay S Pepose4,5 1Department of Ophthalmology, Carle Foundation Hospital, Champaign, IL, USA; 2Chu Eye Institute, Fort Worth, TX, USA; 3Cokingtin Eye Center, Overland Park, KS, USA; 4Pepose Vision Institute, S...

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Autores principales:	Zafar AB, Chu RC, Bishara MN, Qazi MA, Mahmoud AM, Pepose JS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	hd analyzer posterior capsular opacity yag capsulotomy objective scatter index Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/c356409ccf084d9091aa6ff48e67c1db
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spelling	oai:doaj.org-article:c356409ccf084d9091aa6ff48e67c1db2021-12-02T08:19:22ZObjective Quantification of Image Quality and Optical Scatter Before and After Nd:YAG Capsulotomy Using a Double-Pass Technique1177-5483https://doaj.org/article/c356409ccf084d9091aa6ff48e67c1db2020-05-01T00:00:00Zhttps://www.dovepress.com/objective-quantification-of-image-quality-and-optical-scatter-before-a-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Abu-Bakar Zafar,1 Richard C Chu,2 Miranda N Bishara,3 Mujtaba A Qazi,4,5 Ashraf M Mahmoud,6 Jay S Pepose4,5 1Department of Ophthalmology, Carle Foundation Hospital, Champaign, IL, USA; 2Chu Eye Institute, Fort Worth, TX, USA; 3Cokingtin Eye Center, Overland Park, KS, USA; 4Pepose Vision Institute, St. Louis, MO, USA; 5Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA; 6Department of Ophthalmology, Ohio State University, Columbus, OH, USACorrespondence: Jay S PeposePepose Vision Institute, 1815 Clarkson Road, Chesterfield, MO 63107, USAEmail jpepose@peposevision.comPurpose: The purpose of this study is to evaluate and compare the correlation between changes in vision and HD Analyzer dual-pass metrics versus changes in vision and conventional subjective slit lamp gradings in pseudophakic patients with posterior capsular opacity undergoing neodymium:yttrium-aluminum-garnet (Nd:YAG) capsulotomy.Patients and Methods: High contrast (HC) and low contrast (LC) best spectacle-corrected distance visual acuity (BCVA) and HD Analyzer evaluation were prospectively performed on patients with mild-to-moderate posterior capsular opacification (PCO) and monofocal and accommodating intraocular lens implants. Differences between pre- and post-operative measurements were calculated, along with the correlation of HD Analyzer metrics and slit lamp grading to changes in visual acuity.Results: Following Nd:YAG capsulotomy (n=29), there was statistically significant improvement in HC-BCVA and LC-BCVA, decrease in optical scatter, and corresponding improvement in Strehl ratio and HD Analyzer values at all contrast levels tested (p≤ 0.05). Pearson test showed a high correlation between the improvement in HC-BCVA (r coefficient = 0.78) and LC-BCVA (r coefficient = 0.71) to the improvement in Objective Scatter Index (OSI). There was a higher correlation of change in HC-BCVA to pre-op OSI  (r2=0.61) than to the subjective PCO grading score (r2 = 0.19). There was also a higher correlation of change in LC-BCVA to pre-op OSI (r2 = 0.49) than to subjective grading (r2 = 0.16).Conclusion: The HD Analyzer provides objective measurements of forward light scatter (ie, light directed towards the retina) that can assist with both PCO grading and prediction of improvement of visual quality after YAG laser capsulotomy with higher accuracy than conventional slit lamp assessment based upon backscatter (ie, light traveling to the observer) in patients tested with monofocal and accommodating intraocular lens implants.Keywords: HD Analyzer, posterior capsular opacity, YAG capsulotomy, objective scatter indexZafar ABChu RCBishara MNQazi MAMahmoud AMPepose JSDove Medical Pressarticlehd analyzerposterior capsular opacityyag capsulotomyobjective scatter indexOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 1403-1411 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	hd analyzer posterior capsular opacity yag capsulotomy objective scatter index Ophthalmology RE1-994
spellingShingle	hd analyzer posterior capsular opacity yag capsulotomy objective scatter index Ophthalmology RE1-994 Zafar AB Chu RC Bishara MN Qazi MA Mahmoud AM Pepose JS Objective Quantification of Image Quality and Optical Scatter Before and After Nd:YAG Capsulotomy Using a Double-Pass Technique
description	Abu-Bakar Zafar,1 Richard C Chu,2 Miranda N Bishara,3 Mujtaba A Qazi,4,5 Ashraf M Mahmoud,6 Jay S Pepose4,5 1Department of Ophthalmology, Carle Foundation Hospital, Champaign, IL, USA; 2Chu Eye Institute, Fort Worth, TX, USA; 3Cokingtin Eye Center, Overland Park, KS, USA; 4Pepose Vision Institute, St. Louis, MO, USA; 5Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA; 6Department of Ophthalmology, Ohio State University, Columbus, OH, USACorrespondence: Jay S PeposePepose Vision Institute, 1815 Clarkson Road, Chesterfield, MO 63107, USAEmail jpepose@peposevision.comPurpose: The purpose of this study is to evaluate and compare the correlation between changes in vision and HD Analyzer dual-pass metrics versus changes in vision and conventional subjective slit lamp gradings in pseudophakic patients with posterior capsular opacity undergoing neodymium:yttrium-aluminum-garnet (Nd:YAG) capsulotomy.Patients and Methods: High contrast (HC) and low contrast (LC) best spectacle-corrected distance visual acuity (BCVA) and HD Analyzer evaluation were prospectively performed on patients with mild-to-moderate posterior capsular opacification (PCO) and monofocal and accommodating intraocular lens implants. Differences between pre- and post-operative measurements were calculated, along with the correlation of HD Analyzer metrics and slit lamp grading to changes in visual acuity.Results: Following Nd:YAG capsulotomy (n=29), there was statistically significant improvement in HC-BCVA and LC-BCVA, decrease in optical scatter, and corresponding improvement in Strehl ratio and HD Analyzer values at all contrast levels tested (p≤ 0.05). Pearson test showed a high correlation between the improvement in HC-BCVA (r coefficient = 0.78) and LC-BCVA (r coefficient = 0.71) to the improvement in Objective Scatter Index (OSI). There was a higher correlation of change in HC-BCVA to pre-op OSI  (r2=0.61) than to the subjective PCO grading score (r2 = 0.19). There was also a higher correlation of change in LC-BCVA to pre-op OSI (r2 = 0.49) than to subjective grading (r2 = 0.16).Conclusion: The HD Analyzer provides objective measurements of forward light scatter (ie, light directed towards the retina) that can assist with both PCO grading and prediction of improvement of visual quality after YAG laser capsulotomy with higher accuracy than conventional slit lamp assessment based upon backscatter (ie, light traveling to the observer) in patients tested with monofocal and accommodating intraocular lens implants.Keywords: HD Analyzer, posterior capsular opacity, YAG capsulotomy, objective scatter index
format	article
author	Zafar AB Chu RC Bishara MN Qazi MA Mahmoud AM Pepose JS
author_facet	Zafar AB Chu RC Bishara MN Qazi MA Mahmoud AM Pepose JS
author_sort	Zafar AB
title	Objective Quantification of Image Quality and Optical Scatter Before and After Nd:YAG Capsulotomy Using a Double-Pass Technique
title_short	Objective Quantification of Image Quality and Optical Scatter Before and After Nd:YAG Capsulotomy Using a Double-Pass Technique
title_full	Objective Quantification of Image Quality and Optical Scatter Before and After Nd:YAG Capsulotomy Using a Double-Pass Technique
title_fullStr	Objective Quantification of Image Quality and Optical Scatter Before and After Nd:YAG Capsulotomy Using a Double-Pass Technique
title_full_unstemmed	Objective Quantification of Image Quality and Optical Scatter Before and After Nd:YAG Capsulotomy Using a Double-Pass Technique
title_sort	objective quantification of image quality and optical scatter before and after nd:yag capsulotomy using a double-pass technique
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/c356409ccf084d9091aa6ff48e67c1db
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Objective Quantification of Image Quality and Optical Scatter Before and After Nd:YAG Capsulotomy Using a Double-Pass Technique

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