Cerium oxide nanoparticles: green synthesis and biological applications

Fahimeh Charbgoo,1 Mansor Bin Ahmad,2,* Majid Darroudi3,* 1Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran; 2Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 3Nuclear Medicine R...

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Autores principales:	Charbgoo F, Ahmad MB, Darroudi M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Cerium oxide nanoparticles green synthesis biocompatibility nanobiotechnology biological application Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/c358412786fd428192ed4fa60a428e36
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spelling	oai:doaj.org-article:c358412786fd428192ed4fa60a428e362021-12-02T05:14:20ZCerium oxide nanoparticles: green synthesis and biological applications1178-2013https://doaj.org/article/c358412786fd428192ed4fa60a428e362017-02-01T00:00:00Zhttps://www.dovepress.com/cerium-oxide-nanoparticles-green-synthesis-and-biological-applications-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Fahimeh Charbgoo,1 Mansor Bin Ahmad,2,* Majid Darroudi3,* 1Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran; 2Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 3Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran *These authors contributed equally to this work Abstract: CeO2 nanoparticles (NPs) have shown promising approaches as therapeutic agents in biology and medical sciences. The physicochemical properties of CeO2-NPs, such as size, agglomeration status in liquid, and surface charge, play important roles in the ultimate interactions of the NP with target cells. Recently, CeO2-NPs have been synthesized through several bio-directed methods applying natural and organic matrices as stabilizing agents in order to prepare biocompatible CeO2-NPs, thereby solving the challenges regarding safety, and providing the appropriate situation for their effective use in biomedicine. This review discusses the different green strategies for CeO2-NPs synthesis, their advantages and challenges that are to be overcome. In addition, this review focuses on recent progress in the potential application of CeO2-NPs in biological and medical fields. Exploiting biocompatible CeO2-NPs may improve outcomes profoundly with the promise of effective neurodegenerative therapy and multiple applications in nanobiotechnology. Keywords: cerium oxide nanoparticles, green synthesis, biocompatibility, surface Ce3+, size, morphologyCharbgoo FAhmad MBDarroudi MDove Medical PressarticleCerium oxide nanoparticlesgreen synthesisbiocompatibilitynanobiotechnologybiological applicationMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 12, Pp 1401-1413 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Cerium oxide nanoparticles green synthesis biocompatibility nanobiotechnology biological application Medicine (General) R5-920
spellingShingle	Cerium oxide nanoparticles green synthesis biocompatibility nanobiotechnology biological application Medicine (General) R5-920 Charbgoo F Ahmad MB Darroudi M Cerium oxide nanoparticles: green synthesis and biological applications
description	Fahimeh Charbgoo,1 Mansor Bin Ahmad,2,* Majid Darroudi3,* 1Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran; 2Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 3Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran *These authors contributed equally to this work Abstract: CeO2 nanoparticles (NPs) have shown promising approaches as therapeutic agents in biology and medical sciences. The physicochemical properties of CeO2-NPs, such as size, agglomeration status in liquid, and surface charge, play important roles in the ultimate interactions of the NP with target cells. Recently, CeO2-NPs have been synthesized through several bio-directed methods applying natural and organic matrices as stabilizing agents in order to prepare biocompatible CeO2-NPs, thereby solving the challenges regarding safety, and providing the appropriate situation for their effective use in biomedicine. This review discusses the different green strategies for CeO2-NPs synthesis, their advantages and challenges that are to be overcome. In addition, this review focuses on recent progress in the potential application of CeO2-NPs in biological and medical fields. Exploiting biocompatible CeO2-NPs may improve outcomes profoundly with the promise of effective neurodegenerative therapy and multiple applications in nanobiotechnology. Keywords: cerium oxide nanoparticles, green synthesis, biocompatibility, surface Ce3+, size, morphology
format	article
author	Charbgoo F Ahmad MB Darroudi M
author_facet	Charbgoo F Ahmad MB Darroudi M
author_sort	Charbgoo F
title	Cerium oxide nanoparticles: green synthesis and biological applications
title_short	Cerium oxide nanoparticles: green synthesis and biological applications
title_full	Cerium oxide nanoparticles: green synthesis and biological applications
title_fullStr	Cerium oxide nanoparticles: green synthesis and biological applications
title_full_unstemmed	Cerium oxide nanoparticles: green synthesis and biological applications
title_sort	cerium oxide nanoparticles: green synthesis and biological applications
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/c358412786fd428192ed4fa60a428e36
work_keys_str_mv	AT charbgoof ceriumoxidenanoparticlesgreensynthesisandbiologicalapplications AT ahmadmb ceriumoxidenanoparticlesgreensynthesisandbiologicalapplications AT darroudim ceriumoxidenanoparticlesgreensynthesisandbiologicalapplications
_version_	1718400495710633984

Cerium oxide nanoparticles: green synthesis and biological applications

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