Somatic cell hemoglobin modulates nitrogen oxide metabolism in the human airway epithelium

Somatic cell hemoglobin modulates nitrogen oxide metabolism in the human airway epithelium

Abstract Endothelial hemoglobin (Hb)α regulates endothelial nitric oxide synthase (eNOS) biochemistry. We hypothesized that Hb could also be expressed and biochemically active in the ciliated human airway epithelium. Primary human airway epithelial cells, cultured at air–liquid interface (ALI), were...

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Bibliographic Details
Main Authors: Nadzeya Marozkina, Laura Smith, Yi Zhao, Joe Zein, James F. Chmiel, Jeeho Kim, Janna Kiselar, Michael D. Davis, Rebekah S. Cunningham, Scott H. Randell, Benjamin Gaston
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/c3588f16218844d884b6e71832474325
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