Interactions of Monocytes, HIV, and ART Identified by an Innovative scRNAseq Pipeline: Pathways to Reservoirs and HIV-Associated Comorbidities
ABSTRACT HIV reservoirs persist despite successful antiretroviral therapy (ART) and are a major obstacle to the eradication and cure of HIV. The mature monocyte subset, CD14+CD16+, contributes to viral reservoirs and HIV-associated comorbidities. Only a subset of monocytes harbors HIV (HIV+), while...
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Main Authors: | Rosiris León-Rivera, Brenda Morsey, Meng Niu, Howard S. Fox, Joan W. Berman |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2020
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Online Access: | https://doaj.org/article/c358f77e88bb4cdbafccab520569d140 |
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