Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
Being able to regulate gene expression in a controllable manner is one of the promises of synthetic biology, and CRISPR-Cas9 is one of the tools being developed to achieve that goal. Here the authors develop an inducible CRISPR platform using an engineered guide RNA.
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2017
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/c3599b79b8d04d34aa8e0a984e7a35c2 |
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| Résumé: | Being able to regulate gene expression in a controllable manner is one of the promises of synthetic biology, and CRISPR-Cas9 is one of the tools being developed to achieve that goal. Here the authors develop an inducible CRISPR platform using an engineered guide RNA. |
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