Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

Being able to regulate gene expression in a controllable manner is one of the promises of synthetic biology, and CRISPR-Cas9 is one of the tools being developed to achieve that goal. Here the authors develop an inducible CRISPR platform using an engineered guide RNA.

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Auteurs principaux:	Quentin R. V. Ferry, Radostina Lyutova, Tudor A. Fulga
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/c3599b79b8d04d34aa8e0a984e7a35c2
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spelling	oai:doaj.org-article:c3599b79b8d04d34aa8e0a984e7a35c22021-12-02T14:42:24ZRational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs10.1038/ncomms146332041-1723https://doaj.org/article/c3599b79b8d04d34aa8e0a984e7a35c22017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14633https://doaj.org/toc/2041-1723Being able to regulate gene expression in a controllable manner is one of the promises of synthetic biology, and CRISPR-Cas9 is one of the tools being developed to achieve that goal. Here the authors develop an inducible CRISPR platform using an engineered guide RNA.Quentin R. V. FerryRadostina LyutovaTudor A. FulgaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Quentin R. V. Ferry Radostina Lyutova Tudor A. Fulga Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
description	Being able to regulate gene expression in a controllable manner is one of the promises of synthetic biology, and CRISPR-Cas9 is one of the tools being developed to achieve that goal. Here the authors develop an inducible CRISPR platform using an engineered guide RNA.
format	article
author	Quentin R. V. Ferry Radostina Lyutova Tudor A. Fulga
author_facet	Quentin R. V. Ferry Radostina Lyutova Tudor A. Fulga
author_sort	Quentin R. V. Ferry
title	Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
title_short	Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
title_full	Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
title_fullStr	Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
title_full_unstemmed	Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
title_sort	rational design of inducible crispr guide rnas for de novo assembly of transcriptional programs
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/c3599b79b8d04d34aa8e0a984e7a35c2
work_keys_str_mv	AT quentinrvferry rationaldesignofinduciblecrisprguidernasfordenovoassemblyoftranscriptionalprograms AT radostinalyutova rationaldesignofinduciblecrisprguidernasfordenovoassemblyoftranscriptionalprograms AT tudorafulga rationaldesignofinduciblecrisprguidernasfordenovoassemblyoftranscriptionalprograms
_version_	1718389715264077824

Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

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