Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

Being able to regulate gene expression in a controllable manner is one of the promises of synthetic biology, and CRISPR-Cas9 is one of the tools being developed to achieve that goal. Here the authors develop an inducible CRISPR platform using an engineered guide RNA.

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Autores principales: Quentin R. V. Ferry, Radostina Lyutova, Tudor A. Fulga
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/c3599b79b8d04d34aa8e0a984e7a35c2
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