Extinct type of human parvovirus B19 persists in tonsillar B cells

The cell type that hosts parvovirus B19 (B19V) DNA lifelong is currently unknown. Here, the authors identify tonsillar B cells as a reservoir, detect an extinct B19V type in older adults, supporting a long-term association, and show that B19V uptake into B cells is antibody dependent.

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Detalles Bibliográficos
Autores principales: Lari Pyöriä, Mari Toppinen, Elina Mäntylä, Lea Hedman, Leena-Maija Aaltonen, Maija Vihinen-Ranta, Taru Ilmarinen, Maria Söderlund-Venermo, Klaus Hedman, Maria F. Perdomo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c361ff35670e4ffbbdd991ab4dfb34ac
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