Fate of lymphocytes after withdrawal of tofacitinib treatment.

Tofacitinib (Tofa) is an inhibitor of Janus Kinase 3, developed for the treatment of autoimmune diseases and for the prevention of transplant rejection. Due to its selective action on proliferating cells, Tofa can offer a way to block T cell activation, without toxic effects on resting cells. Howeve...

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Autores principales: Elisa Piscianz, Erica Valencic, Eva Cuzzoni, Sara De Iudicibus, Elisa De Lorenzo, Giuliana Decorti, Alberto Tommasini
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/c368fa2460f142dba23c19f4c39d15f0
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