p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1.

p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1.

During the first weeks of postnatal heart development, cardiomyocytes undergo a major adaptive metabolic shift from glycolytic energy production to fatty acid oxidation. This metabolic change is contemporaneous to the up-regulation and activation of the p38γ and p38δ stress-activated protein kinases...

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Auteurs principaux: Ayelén M Santamans, Valle Montalvo-Romeral, Alfonso Mora, Juan Antonio Lopez, Francisco González-Romero, Daniel Jimenez-Blasco, Elena Rodríguez, Aránzazu Pintor-Chocano, Cristina Casanueva-Benítez, Rebeca Acín-Pérez, Luis Leiva-Vega, Jordi Duran, Joan J Guinovart, Jesús Jiménez-Borreguero, José Antonio Enríquez, María Villlalba-Orero, Juan P Bolaños, Patricia Aspichueta, Jesús Vázquez, Bárbara González-Terán, Guadalupe Sabio
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
Sujets:
Biology (General)
QH301-705.5
Accès en ligne:https://doaj.org/article/c36e9e81543246be91c8817f25d367e5
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https://doaj.org/article/c36e9e81543246be91c8817f25d367e5

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