Ex vivo culture of intact human patient derived pancreatic tumour tissue
Abstract The poor prognosis of pancreatic ductal adenocarcinoma (PDAC) is attributed to the highly fibrotic stroma and complex multi-cellular microenvironment that is difficult to fully recapitulate in pre-clinical models. To fast-track translation of therapies and to inform personalised medicine, w...
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Autores principales: | John Kokkinos, George Sharbeen, Koroush S. Haghighi, Rosa Mistica C. Ignacio, Chantal Kopecky, Estrella Gonzales-Aloy, Janet Youkhana, Paul Timpson, Brooke A. Pereira, Shona Ritchie, Elvis Pandzic, Cyrille Boyer, Thomas P. Davis, Lisa M. Butler, David Goldstein, Joshua A. McCarroll, Phoebe A. Phillips |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c376c5a5ce784e57bf7955dbb27bd3ff |
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