Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
Abstract Krabbe disease (KD) is a neurodegenerative disorder caused by the lack of β- galactosylceramidase enzymatic activity and by widespread accumulation of the cytotoxic galactosyl-sphingosine in neuronal, myelinating and endothelial cells. Despite the wide use of Twitcher mice as experimental m...
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Autores principales: | , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2016
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Acceso en línea: | https://doaj.org/article/c37d72751ae0467d9065e594228807fd |
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