G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression

Cheng, Fan, Li et al. identified ANGPTL4 as a G1-induced target gene of GPER/YAP in HRT8 cells using RNA-seq and highlighted its importance in regulating trophoblast cell invasion. The authors also reported GPER downregulation in the placenta and lower estradiol levels in patients who developed pree...

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Autores principales:	Jung-Chien Cheng, Lanlan Fang, Yuxi Li, Avinash Thakur, Pamela A. Hoodless, Yanjie Guo, Zhen Wang, Ze Wu, Yang Yan, Qiongqiong Jia, Yibo Gao, Xiaoyu Han, Yiping Yu, Ying-Pu Sun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/c3858db132154bb18f592d1b774c2406
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spelling	oai:doaj.org-article:c3858db132154bb18f592d1b774c24062021-11-14T12:12:21ZG protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression10.1038/s42003-021-02816-52399-3642https://doaj.org/article/c3858db132154bb18f592d1b774c24062021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02816-5https://doaj.org/toc/2399-3642Cheng, Fan, Li et al. identified ANGPTL4 as a G1-induced target gene of GPER/YAP in HRT8 cells using RNA-seq and highlighted its importance in regulating trophoblast cell invasion. The authors also reported GPER downregulation in the placenta and lower estradiol levels in patients who developed preeclampsia.Jung-Chien ChengLanlan FangYuxi LiAvinash ThakurPamela A. HoodlessYanjie GuoZhen WangZe WuYang YanQiongqiong JiaYibo GaoXiaoyu HanYiping YuYing-Pu SunNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Jung-Chien Cheng Lanlan Fang Yuxi Li Avinash Thakur Pamela A. Hoodless Yanjie Guo Zhen Wang Ze Wu Yang Yan Qiongqiong Jia Yibo Gao Xiaoyu Han Yiping Yu Ying-Pu Sun G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression
description	Cheng, Fan, Li et al. identified ANGPTL4 as a G1-induced target gene of GPER/YAP in HRT8 cells using RNA-seq and highlighted its importance in regulating trophoblast cell invasion. The authors also reported GPER downregulation in the placenta and lower estradiol levels in patients who developed preeclampsia.
format	article
author	Jung-Chien Cheng Lanlan Fang Yuxi Li Avinash Thakur Pamela A. Hoodless Yanjie Guo Zhen Wang Ze Wu Yang Yan Qiongqiong Jia Yibo Gao Xiaoyu Han Yiping Yu Ying-Pu Sun
author_facet	Jung-Chien Cheng Lanlan Fang Yuxi Li Avinash Thakur Pamela A. Hoodless Yanjie Guo Zhen Wang Ze Wu Yang Yan Qiongqiong Jia Yibo Gao Xiaoyu Han Yiping Yu Ying-Pu Sun
author_sort	Jung-Chien Cheng
title	G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression
title_short	G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression
title_full	G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression
title_fullStr	G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression
title_full_unstemmed	G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression
title_sort	g protein-coupled estrogen receptor stimulates human trophoblast cell invasion via yap-mediated angptl4 expression
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c3858db132154bb18f592d1b774c2406
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G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression

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