G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression

G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression

Cheng, Fan, Li et al. identified ANGPTL4 as a G1-induced target gene of GPER/YAP in HRT8 cells using RNA-seq and highlighted its importance in regulating trophoblast cell invasion. The authors also reported GPER downregulation in the placenta and lower estradiol levels in patients who developed pree...

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Autores principales: Jung-Chien Cheng, Lanlan Fang, Yuxi Li, Avinash Thakur, Pamela A. Hoodless, Yanjie Guo, Zhen Wang, Ze Wu, Yang Yan, Qiongqiong Jia, Yibo Gao, Xiaoyu Han, Yiping Yu, Ying-Pu Sun
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/c3858db132154bb18f592d1b774c2406
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