Therapeutic effectiveness of Ocimum basilicum extract on bovine cutaneous papillomatosis

Bovine cutaneous papillomatosis is a common cutaneous disease of cattle in the Egyptian veterinary field. Ocimum basilicum L. (Rehan) is one of the aromatic plants originating in Asia and Africa. Many studies showed that Ocimum basilicum has interesting antiviral and anticancer activities. However...

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Autores principales:	AbdulRahman A. Saied, Ashraf A. El-Ghoneimy, Abdel-latif Seddek, Sary Kh. AbdelGhafar, Samy A.F. Morad
Formato:	article
Lenguaje:	EN
Publicado:	South Valley University 2020
Materias:	basil leaf (ocimum basilicum) clinicopathological bovine cutaneous papillomatosis effectiveness Agriculture S Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/c3907297413443dbb077f66c9414bcd5
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spelling	oai:doaj.org-article:c3907297413443dbb077f66c9414bcd52021-12-02T13:58:29ZTherapeutic effectiveness of Ocimum basilicum extract on bovine cutaneous papillomatosis10.21608/svu.2020.35596.10672535-18262535-1877https://doaj.org/article/c3907297413443dbb077f66c9414bcd52020-09-01T00:00:00Zhttps://svu.journals.ekb.eg/article_112992.htmlhttps://doaj.org/toc/2535-1826https://doaj.org/toc/2535-1877Bovine cutaneous papillomatosis is a common cutaneous disease of cattle in the Egyptian veterinary field. Ocimum basilicum L. (Rehan) is one of the aromatic plants originating in Asia and Africa. Many studies showed that Ocimum basilicum has interesting antiviral and anticancer activities. However, there is no report demonstrating the clinical significance of the anti-papilloma activity of Ocimum basilicum against bovine skin papillomas. Thus, our study was designed to evaluate the therapeutic potential of Ocimum basilicum extract (OBEx) as an anti-papilloma agent against bovine papillomatosis. OBEx was prepared and undergone phytochemical analysis that revealed presence of alkaloids, phenolics, and flavonoids. Ten cutaneous papillomatosis-infected cattle were diagnosed clinically and histopathologically. Animals were treated with OBEx ointment 2% that topically applied daily and papillomas regression was recorded weekly. Clinically, papillomas started to disappear from the 7th - 21st day after the start of treatment. Histopathological analysis showed improvement in histological features of wart tissue returning to the normal skin structure with presence of lymphocytic infiltration. We concluded that the topical application of OBEx is an effective, promising alternative, cheap, and easily apply agent for treatment of skin papilloma. AbdulRahman A. Saied Ashraf A. El-GhoneimyAbdel-latif SeddekSary Kh. AbdelGhafar Samy A.F. MoradSouth Valley Universityarticlebasil leaf (ocimum basilicum)clinicopathologicalbovine cutaneous papillomatosiseffectivenessAgricultureSVeterinary medicineSF600-1100ENSVU-International Journal of Veterinary Sciences, Vol 3, Iss 2, Pp 60-77 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	basil leaf (ocimum basilicum) clinicopathological bovine cutaneous papillomatosis effectiveness Agriculture S Veterinary medicine SF600-1100
spellingShingle	basil leaf (ocimum basilicum) clinicopathological bovine cutaneous papillomatosis effectiveness Agriculture S Veterinary medicine SF600-1100 AbdulRahman A. Saied Ashraf A. El-Ghoneimy Abdel-latif Seddek Sary Kh. AbdelGhafar Samy A.F. Morad Therapeutic effectiveness of Ocimum basilicum extract on bovine cutaneous papillomatosis
description	Bovine cutaneous papillomatosis is a common cutaneous disease of cattle in the Egyptian veterinary field. Ocimum basilicum L. (Rehan) is one of the aromatic plants originating in Asia and Africa. Many studies showed that Ocimum basilicum has interesting antiviral and anticancer activities. However, there is no report demonstrating the clinical significance of the anti-papilloma activity of Ocimum basilicum against bovine skin papillomas. Thus, our study was designed to evaluate the therapeutic potential of Ocimum basilicum extract (OBEx) as an anti-papilloma agent against bovine papillomatosis. OBEx was prepared and undergone phytochemical analysis that revealed presence of alkaloids, phenolics, and flavonoids. Ten cutaneous papillomatosis-infected cattle were diagnosed clinically and histopathologically. Animals were treated with OBEx ointment 2% that topically applied daily and papillomas regression was recorded weekly. Clinically, papillomas started to disappear from the 7th - 21st day after the start of treatment. Histopathological analysis showed improvement in histological features of wart tissue returning to the normal skin structure with presence of lymphocytic infiltration. We concluded that the topical application of OBEx is an effective, promising alternative, cheap, and easily apply agent for treatment of skin papilloma.
format	article
author	AbdulRahman A. Saied Ashraf A. El-Ghoneimy Abdel-latif Seddek Sary Kh. AbdelGhafar Samy A.F. Morad
author_facet	AbdulRahman A. Saied Ashraf A. El-Ghoneimy Abdel-latif Seddek Sary Kh. AbdelGhafar Samy A.F. Morad
author_sort	AbdulRahman A. Saied
title	Therapeutic effectiveness of Ocimum basilicum extract on bovine cutaneous papillomatosis
title_short	Therapeutic effectiveness of Ocimum basilicum extract on bovine cutaneous papillomatosis
title_full	Therapeutic effectiveness of Ocimum basilicum extract on bovine cutaneous papillomatosis
title_fullStr	Therapeutic effectiveness of Ocimum basilicum extract on bovine cutaneous papillomatosis
title_full_unstemmed	Therapeutic effectiveness of Ocimum basilicum extract on bovine cutaneous papillomatosis
title_sort	therapeutic effectiveness of ocimum basilicum extract on bovine cutaneous papillomatosis
publisher	South Valley University
publishDate	2020
url	https://doaj.org/article/c3907297413443dbb077f66c9414bcd5
work_keys_str_mv	AT abdulrahmanasaied therapeuticeffectivenessofocimumbasilicumextractonbovinecutaneouspapillomatosis AT ashrafaelghoneimy therapeuticeffectivenessofocimumbasilicumextractonbovinecutaneouspapillomatosis AT abdellatifseddek therapeuticeffectivenessofocimumbasilicumextractonbovinecutaneouspapillomatosis AT sarykhabdelghafar therapeuticeffectivenessofocimumbasilicumextractonbovinecutaneouspapillomatosis AT samyafmorad therapeuticeffectivenessofocimumbasilicumextractonbovinecutaneouspapillomatosis
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Therapeutic effectiveness of Ocimum basilicum extract on bovine cutaneous papillomatosis

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