Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy

Label-free and real-time visualization of the tumor microenvironment is attractive but challenging. Here the authors present an approach for simultaneous autofluorescence functional imaging and second/third harmonic generation imaging of structural features, using a single excitation source.

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Autores principales: Sixian You, Haohua Tu, Eric J. Chaney, Yi Sun, Youbo Zhao, Andrew J. Bower, Yuan-Zhi Liu, Marina Marjanovic, Saurabh Sinha, Yang Pu, Stephen A. Boppart
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c390f51869424e149f08c881c3e09481
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spelling oai:doaj.org-article:c390f51869424e149f08c881c3e094812021-12-02T17:32:48ZIntravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy10.1038/s41467-018-04470-82041-1723https://doaj.org/article/c390f51869424e149f08c881c3e094812018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04470-8https://doaj.org/toc/2041-1723Label-free and real-time visualization of the tumor microenvironment is attractive but challenging. Here the authors present an approach for simultaneous autofluorescence functional imaging and second/third harmonic generation imaging of structural features, using a single excitation source.Sixian YouHaohua TuEric J. ChaneyYi SunYoubo ZhaoAndrew J. BowerYuan-Zhi LiuMarina MarjanovicSaurabh SinhaYang PuStephen A. BoppartNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sixian You
Haohua Tu
Eric J. Chaney
Yi Sun
Youbo Zhao
Andrew J. Bower
Yuan-Zhi Liu
Marina Marjanovic
Saurabh Sinha
Yang Pu
Stephen A. Boppart
Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy
description Label-free and real-time visualization of the tumor microenvironment is attractive but challenging. Here the authors present an approach for simultaneous autofluorescence functional imaging and second/third harmonic generation imaging of structural features, using a single excitation source.
format article
author Sixian You
Haohua Tu
Eric J. Chaney
Yi Sun
Youbo Zhao
Andrew J. Bower
Yuan-Zhi Liu
Marina Marjanovic
Saurabh Sinha
Yang Pu
Stephen A. Boppart
author_facet Sixian You
Haohua Tu
Eric J. Chaney
Yi Sun
Youbo Zhao
Andrew J. Bower
Yuan-Zhi Liu
Marina Marjanovic
Saurabh Sinha
Yang Pu
Stephen A. Boppart
author_sort Sixian You
title Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy
title_short Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy
title_full Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy
title_fullStr Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy
title_full_unstemmed Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy
title_sort intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/c390f51869424e149f08c881c3e09481
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