Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia risk

Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia risk

The authors provide a comprehensive, single base resolution view of association between genetic variation and DNA methylation in human brain. They also show that heritability attributed to schizophrenia GWAS-associated variants reflects the epigenetic plasticity of the brain.

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Detalles Bibliográficos
Autores principales: Kira A. Perzel Mandell, Nicholas J. Eagles, Richard Wilton, Amanda J. Price, Stephen A. Semick, Leonardo Collado-Torres, William S. Ulrich, Ran Tao, Shizhong Han, Alexander S. Szalay, Thomas M. Hyde, Joel E. Kleinman, Daniel R. Weinberger, Andrew E. Jaffe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
Q
Acceso en línea:https://doaj.org/article/c39209296bd643a888732cfc9a82670a
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https://doaj.org/article/c39209296bd643a888732cfc9a82670a

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