A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation

Combining artificial and natural enzymes is a strategy to mimic biocatalytic processes with high efficiency and selectivity. This study reports a dual catalytic system composed of flavin adenine dinucleotide model and NADH mimics to catalyze the monooxygenation of cyclobutanones and thioethers.

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Auteurs principaux: Liang Zhao, Junkai Cai, Yanan Li, Jianwei Wei, Chunying Duan
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/c396ecb45c474c36be83643bafc15810
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spelling oai:doaj.org-article:c396ecb45c474c36be83643bafc158102021-12-02T14:58:13ZA host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation10.1038/s41467-020-16714-72041-1723https://doaj.org/article/c396ecb45c474c36be83643bafc158102020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16714-7https://doaj.org/toc/2041-1723Combining artificial and natural enzymes is a strategy to mimic biocatalytic processes with high efficiency and selectivity. This study reports a dual catalytic system composed of flavin adenine dinucleotide model and NADH mimics to catalyze the monooxygenation of cyclobutanones and thioethers.Liang ZhaoJunkai CaiYanan LiJianwei WeiChunying DuanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Liang Zhao
Junkai Cai
Yanan Li
Jianwei Wei
Chunying Duan
A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation
description Combining artificial and natural enzymes is a strategy to mimic biocatalytic processes with high efficiency and selectivity. This study reports a dual catalytic system composed of flavin adenine dinucleotide model and NADH mimics to catalyze the monooxygenation of cyclobutanones and thioethers.
format article
author Liang Zhao
Junkai Cai
Yanan Li
Jianwei Wei
Chunying Duan
author_facet Liang Zhao
Junkai Cai
Yanan Li
Jianwei Wei
Chunying Duan
author_sort Liang Zhao
title A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation
title_short A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation
title_full A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation
title_fullStr A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation
title_full_unstemmed A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation
title_sort host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c396ecb45c474c36be83643bafc15810
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