A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation
Combining artificial and natural enzymes is a strategy to mimic biocatalytic processes with high efficiency and selectivity. This study reports a dual catalytic system composed of flavin adenine dinucleotide model and NADH mimics to catalyze the monooxygenation of cyclobutanones and thioethers.
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2020
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oai:doaj.org-article:c396ecb45c474c36be83643bafc158102021-12-02T14:58:13ZA host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation10.1038/s41467-020-16714-72041-1723https://doaj.org/article/c396ecb45c474c36be83643bafc158102020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16714-7https://doaj.org/toc/2041-1723Combining artificial and natural enzymes is a strategy to mimic biocatalytic processes with high efficiency and selectivity. This study reports a dual catalytic system composed of flavin adenine dinucleotide model and NADH mimics to catalyze the monooxygenation of cyclobutanones and thioethers.Liang ZhaoJunkai CaiYanan LiJianwei WeiChunying DuanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Liang Zhao Junkai Cai Yanan Li Jianwei Wei Chunying Duan A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation |
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Combining artificial and natural enzymes is a strategy to mimic biocatalytic processes with high efficiency and selectivity. This study reports a dual catalytic system composed of flavin adenine dinucleotide model and NADH mimics to catalyze the monooxygenation of cyclobutanones and thioethers. |
format |
article |
author |
Liang Zhao Junkai Cai Yanan Li Jianwei Wei Chunying Duan |
author_facet |
Liang Zhao Junkai Cai Yanan Li Jianwei Wei Chunying Duan |
author_sort |
Liang Zhao |
title |
A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation |
title_short |
A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation |
title_full |
A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation |
title_fullStr |
A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation |
title_full_unstemmed |
A host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation |
title_sort |
host–guest approach to combining enzymatic and artificial catalysis for catalyzing biomimetic monooxygenation |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/c396ecb45c474c36be83643bafc15810 |
work_keys_str_mv |
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