Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses

Jeffery Schafer,1 William Reindel,1 Robert Steffen,1 Gary Mosehauer,1 Joseph Chinn2 1Vision Care, Bausch and Lomb Incorporated, Rochester, NY, USA; 2J Chinn LLC, Lafayette, CO, USA Background: Sustained digital display viewing reduces eye blink frequency and tear film stability. To retain water an...

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Autores principales:	Schafer J, Reindel W, Steffen R, Mosehauer G, Chinn J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	polyvinylpyrrolidone (PVP) digital video display extended blink time (EBT) visual quality (VQ) lens hydration Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/c399917cc92542b2a612b4a8c3db7cd2
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spelling	oai:doaj.org-article:c399917cc92542b2a612b4a8c3db7cd22021-12-02T00:38:51ZUse of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses1177-5483https://doaj.org/article/c399917cc92542b2a612b4a8c3db7cd22018-05-01T00:00:00Zhttps://www.dovepress.com/use-of-a-novel-extended-blink-test-to-evaluate-the-performance-of-two--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Jeffery Schafer,1 William Reindel,1 Robert Steffen,1 Gary Mosehauer,1 Joseph Chinn2 1Vision Care, Bausch and Lomb Incorporated, Rochester, NY, USA; 2J Chinn LLC, Lafayette, CO, USA Background: Sustained digital display viewing reduces eye blink frequency and tear film stability. To retain water and preserve a smooth optical surface, contact lens manufacturers have integrated the humectant polyvinylpyrrolidone (PVP) into silicone hydrogel contact lenses. In this study, extended blink time (EBT) was used to assess visual stability over a prolonged blink interval of two PVP-containing silicone hydrogel lenses, samfilcon A (SAM) and senofilcon A (SEN).Materials and methods: This randomized, bilateral, masked, crossover study assessed lens performance in ten subjects after 16 hours of wear. EBT, ie, the time elapsed between cessation of blinking and blur-out of a threshold letter on the acuity chart, was measured. At the end of the wear period, subjects reported duration of computer use and rated visual quality (VQ) and comfort while wearing the assigned lens, and the investigator evaluated lens surface wetting characteristics. Each lens was removed and immediately weighed to determine total water content.Results: EBTs were 10.42 seconds for SAM and 8.04 seconds for SEN (p = 0.015). Subjective ratings of VQ after 16 hours of wear were 84.6 for SAM and 74.4 for SEN (p = 0.049). Comfort ratings were 85.9 for SAM and 80.2 for SEN (p > 0.05). Median times of computer use were 6–8 hours for both lens types. Post blink, 70.0% of SAM and 30.0% of SEN lenses were completely wet (p = 0.021). Total water content after wear was 43.7% for SAM and 35.5% for SEN (p < 0.001).Conclusion: EBT measurement indicated more stable vision with the PVP-containing SAM polymer compared with the PVP-containing SEN polymer. The SAM polymer also demonstrated better surface wetting and maintained higher water content after a prolonged period of wear. EBT can be valuable in assessing vision stability of patients after hours of computer use. Keywords: polyvinylpyrrolidone, PVP, digital video display, extended blink time, EBT, visual quality, VQ, lens hydrationSchafer JReindel WSteffen RMosehauer GChinn JDove Medical Pressarticlepolyvinylpyrrolidone (PVP)digital video displayextended blink time (EBT)visual quality (VQ)lens hydrationOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 819-825 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	polyvinylpyrrolidone (PVP) digital video display extended blink time (EBT) visual quality (VQ) lens hydration Ophthalmology RE1-994
spellingShingle	polyvinylpyrrolidone (PVP) digital video display extended blink time (EBT) visual quality (VQ) lens hydration Ophthalmology RE1-994 Schafer J Reindel W Steffen R Mosehauer G Chinn J Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses
description	Jeffery Schafer,1 William Reindel,1 Robert Steffen,1 Gary Mosehauer,1 Joseph Chinn2 1Vision Care, Bausch and Lomb Incorporated, Rochester, NY, USA; 2J Chinn LLC, Lafayette, CO, USA Background: Sustained digital display viewing reduces eye blink frequency and tear film stability. To retain water and preserve a smooth optical surface, contact lens manufacturers have integrated the humectant polyvinylpyrrolidone (PVP) into silicone hydrogel contact lenses. In this study, extended blink time (EBT) was used to assess visual stability over a prolonged blink interval of two PVP-containing silicone hydrogel lenses, samfilcon A (SAM) and senofilcon A (SEN).Materials and methods: This randomized, bilateral, masked, crossover study assessed lens performance in ten subjects after 16 hours of wear. EBT, ie, the time elapsed between cessation of blinking and blur-out of a threshold letter on the acuity chart, was measured. At the end of the wear period, subjects reported duration of computer use and rated visual quality (VQ) and comfort while wearing the assigned lens, and the investigator evaluated lens surface wetting characteristics. Each lens was removed and immediately weighed to determine total water content.Results: EBTs were 10.42 seconds for SAM and 8.04 seconds for SEN (p = 0.015). Subjective ratings of VQ after 16 hours of wear were 84.6 for SAM and 74.4 for SEN (p = 0.049). Comfort ratings were 85.9 for SAM and 80.2 for SEN (p > 0.05). Median times of computer use were 6–8 hours for both lens types. Post blink, 70.0% of SAM and 30.0% of SEN lenses were completely wet (p = 0.021). Total water content after wear was 43.7% for SAM and 35.5% for SEN (p < 0.001).Conclusion: EBT measurement indicated more stable vision with the PVP-containing SAM polymer compared with the PVP-containing SEN polymer. The SAM polymer also demonstrated better surface wetting and maintained higher water content after a prolonged period of wear. EBT can be valuable in assessing vision stability of patients after hours of computer use. Keywords: polyvinylpyrrolidone, PVP, digital video display, extended blink time, EBT, visual quality, VQ, lens hydration
format	article
author	Schafer J Reindel W Steffen R Mosehauer G Chinn J
author_facet	Schafer J Reindel W Steffen R Mosehauer G Chinn J
author_sort	Schafer J
title	Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses
title_short	Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses
title_full	Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses
title_fullStr	Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses
title_full_unstemmed	Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses
title_sort	use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/c399917cc92542b2a612b4a8c3db7cd2
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Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses

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