Virchow’s Triad and the Role of Thrombosis in COVID-Related Stroke

In December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as a virally transmitted disease. Three months later, SARS-CoV-2 became one of the largest pandemics in recent times, causing more than 235 million cases globally, and accounting for at least 4.8 million de...

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Autores principales:	Francisco J. Gonzalez-Gonzalez, Mary Rodriguez Ziccardi, Mark D. McCauley
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	COVID-19 stroke Virchow’s triad thrombosis cardiovascular Physiology QP1-981
Acceso en línea:	https://doaj.org/article/c399ed6b02fe480e810eb62f9c72095a
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spelling	oai:doaj.org-article:c399ed6b02fe480e810eb62f9c72095a2021-11-10T08:01:48ZVirchow’s Triad and the Role of Thrombosis in COVID-Related Stroke1664-042X10.3389/fphys.2021.769254https://doaj.org/article/c399ed6b02fe480e810eb62f9c72095a2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fphys.2021.769254/fullhttps://doaj.org/toc/1664-042XIn December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as a virally transmitted disease. Three months later, SARS-CoV-2 became one of the largest pandemics in recent times, causing more than 235 million cases globally, and accounting for at least 4.8 million deaths to date. SARS-COV-2 infection was initially classified as a respiratory tract infection, but later was recognized as a multisystemic disease compromising gastrointestinal, hematological, cardiac, and neurological systems. With this Review, we aim to describe the epidemiology, risk factors, mechanisms, and management of cerebrovascular events in patients infected with COVID-19. Neurological manifestations related to thromboembolic cerebrovascular events in patients infected with COVID-19 have been frequent and associated with poor prognosis in the majority of cases. A better understanding of the mechanisms of thrombosis and etiologies of this new disease process are necessary to determine how to prevent and treat patients to reduce their length of stay, morbidity, and mortality.Francisco J. Gonzalez-GonzalezMary Rodriguez ZiccardiMary Rodriguez ZiccardiMark D. McCauleyMark D. McCauleyMark D. McCauleyFrontiers Media S.A.articleCOVID-19strokeVirchow’s triadthrombosiscardiovascularPhysiologyQP1-981ENFrontiers in Physiology, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 stroke Virchow’s triad thrombosis cardiovascular Physiology QP1-981
spellingShingle	COVID-19 stroke Virchow’s triad thrombosis cardiovascular Physiology QP1-981 Francisco J. Gonzalez-Gonzalez Mary Rodriguez Ziccardi Mary Rodriguez Ziccardi Mark D. McCauley Mark D. McCauley Mark D. McCauley Virchow’s Triad and the Role of Thrombosis in COVID-Related Stroke
description	In December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as a virally transmitted disease. Three months later, SARS-CoV-2 became one of the largest pandemics in recent times, causing more than 235 million cases globally, and accounting for at least 4.8 million deaths to date. SARS-COV-2 infection was initially classified as a respiratory tract infection, but later was recognized as a multisystemic disease compromising gastrointestinal, hematological, cardiac, and neurological systems. With this Review, we aim to describe the epidemiology, risk factors, mechanisms, and management of cerebrovascular events in patients infected with COVID-19. Neurological manifestations related to thromboembolic cerebrovascular events in patients infected with COVID-19 have been frequent and associated with poor prognosis in the majority of cases. A better understanding of the mechanisms of thrombosis and etiologies of this new disease process are necessary to determine how to prevent and treat patients to reduce their length of stay, morbidity, and mortality.
format	article
author	Francisco J. Gonzalez-Gonzalez Mary Rodriguez Ziccardi Mary Rodriguez Ziccardi Mark D. McCauley Mark D. McCauley Mark D. McCauley
author_facet	Francisco J. Gonzalez-Gonzalez Mary Rodriguez Ziccardi Mary Rodriguez Ziccardi Mark D. McCauley Mark D. McCauley Mark D. McCauley
author_sort	Francisco J. Gonzalez-Gonzalez
title	Virchow’s Triad and the Role of Thrombosis in COVID-Related Stroke
title_short	Virchow’s Triad and the Role of Thrombosis in COVID-Related Stroke
title_full	Virchow’s Triad and the Role of Thrombosis in COVID-Related Stroke
title_fullStr	Virchow’s Triad and the Role of Thrombosis in COVID-Related Stroke
title_full_unstemmed	Virchow’s Triad and the Role of Thrombosis in COVID-Related Stroke
title_sort	virchow’s triad and the role of thrombosis in covid-related stroke
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/c399ed6b02fe480e810eb62f9c72095a
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Virchow’s Triad and the Role of Thrombosis in COVID-Related Stroke

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