Transcriptome Analysis of Insulin Signaling-Associated Transcription Factors in <i>C. elegans</i> Reveal Their Genome-Wide Target Genes Specificity and Complexity
Insulin/IGF-1-like signaling (IIS) plays a crucial, conserved role in development, growth, reproduction, stress tolerance, and longevity. In <i>Caenorhabditis elegans,</i> the enhanced longevity under reduced insulin signaling (rIIS) is primarily regulated by the transcription factors (T...
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Autores principales: | , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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MDPI AG
2021
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Acceso en línea: | https://doaj.org/article/c3a9ea83753a4049a93684ce7b38e681 |
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