iNOS promotes hypothalamic insulin resistance associated with deregulation of energy balance and obesity in rodents

Abstract Inducible nitric oxide (iNOS)-mediated S-nitrosation of the metabolic signaling pathway has emerged as a post-translational modification that triggers insulin resistance in obesity and aging. However, the effects of S-nitrosation in controlling energy homeostasis are unknown. Thus, in the p...

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Autores principales: Carlos Kiyoshi Katashima, Vagner Ramon Rodrigues Silva, Luciene Lenhare, Rodrigo Miguel Marin, José Barreto Campello Carvalheira
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c3aa083aeca14bd2aebfe2399c96cba1
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